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2023
Role of signal transduction pathways in IL‐1β‐induced apoptosis: Pathological and therapeutic aspects
Immunity, Inflammation and Disease
2023
Pathogenesis and therapeutic implications of matrix metalloproteinases in intervertebral disc degeneration: A comprehensive review
Biochimie
2023
Low back pain and osteoarthritis pain: a perspective of estrogen
Bone Research
2022
Anti-Degenerative Effect of Melatonin on Intervertebral Disc: Protective Contribution against Inflammation, Oxidative Stress, Apoptosis, and Autophagy
Current Drug Targets
2022
Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m6A Modification of MAT2A Pre-mRNA by METTL16
Oxidative Medicine and Cellular Longevity
2022
Pharmacological Effects of Resveratrol in Intervertebral Disc Degeneration: A Literature Review
Orthopaedic Surgery
2022
The Role of Oxidative Stress in Intervertebral Disc Degeneration
Oxidative Medicine and Cellular Longevity
2022
Research Progress of PI3K/AKT Signaling Pathway in Intervertebral Disc Degeneration
Advances in Clinical Medicine
2022
Antioxidant Effects of Resveratrol in Intervertebral Disk
Journal of Investigative Surgery
2022
Disease-associated regulation of gene expression by resveratrol: Special focus on the PI3K/AKT signaling pathway
Cancer Cell International
2021
Multiscale Regulation of the Intervertebral Disc: Achievements in Experimental, In Silico, and Regenerative Research
International Journal of Molecular Sciences
2021
Resveratrol Suppresses Annulus Fibrosus Cell Apoptosis through Regulating Oxidative Stress Reaction in an Inflammatory Environment
BioMed Research International
2021
Resveratrol protects human nucleus pulposus cells from degeneration by blocking IL-6/JAK/STAT3 pathway
European Journal of Medical Research
2021
Natural Products of Pharmacology and Mechanisms in Nucleus Pulposus Cells and Intervertebral Disc Degeneration
Evidence-Based Complementary and Alternative Medicine
2021
Pharmacological inhibition of mTORC1 activity protects against inflammation-induced apoptosis of nucleus pulposus cells
Brazilian Journal of Medical and Biological Research
2021
Resveratrol Combined with 17β-Estradiol Prevents IL-1β Induced Apoptosis in Human Nucleus Pulposus Via The PI3K/AKT/Mtor and PI3K/AKT/GSK-3β Pathway
Journal of Investigative Surgery
2020
17β-Estradiol Prevents Extracellular Matrix Degradation by Downregulating MMP3 Expression via PI3K/Akt/FOXO3 Pathway
Spine
2020
Resveratrol protects against apoptosis induced by interleukin-1β in nucleus pulposus cells via activating mTOR/caspase-3 and GSK-3β/caspase-3 pathways
Bioscience Reports
2020
Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen
Ageing Research Reviews
2019
Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway
Bioscience Reports
2019
Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway
Bioscience Reports
2019
miRNA‑766 induces apoptosis of human colon cancer cells through the p53/Bax signaling pathway by MDM4
Experimental and Therapeutic Medicine
2019
17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway
Molecular Medicine Reports
2019
Resveratrol in management of bone and spinal cancers
Natural Product Research
2018
Potential therapeutic role of Co-Q10 in alleviating intervertebral disc degeneration and suppressing IL-1β-mediated inflammatory reaction in NP cells
International Immunopharmacology
2018
Dehydrocostus lactone suppresses cell growth and induces apoptosis in recombinant human papilloma virus‑18 HaCaT cells via the PI3K/Akt signaling pathway
Molecular Medicine Reports
2018
Resveratrol provides neuroprotection by regulating the JAK2/STAT3/PI3K/AKT/mTOR pathway after stroke in rats
Genes & Diseases
2018
17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition
Biomedicine & Pharmacotherapy
2018
Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway
Bioscience Reports
2018
FcγRIIB receptor-mediated apoptosis in macrophages through interplay of cadmium sulfide nanomaterials and protein corona
Ecotoxicology and Environmental Safety
2018
Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture
Bioscience Reports
2018
Osteogenic protein-1 attenuates nucleus pulposus cell apoptosis through activating the PI3K/Akt/mTOR pathway in a hyperosmotic culture
Bioscience Reports
2018
Osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high magnitude compression though inhibiting the p38 MAPK pathway
Bioscience Reports
2017
Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway
Oncotarget
2017
Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture
Bioscience Reports
2017
Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway
Evidence-Based Complementary and Alternative Medicine
2017
The PI3K/Akt pathway: a critical player in intervertebral disc degeneration
Oncotarget
2017
Protective role of 17β-estradiol on tumor necrosis factor-α-induced apoptosis in human nucleus pulposus cells
Molecular Medicine Reports
2017
ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration
Oxidative Medicine and Cellular Longevity
2017
N‑cadherin attenuates nucleus pulposus cell senescence under high‑magnitude compression
Molecular Medicine Reports
2016
17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway
Medical Science Monitor
2016
RACK1 overexpression associates with pancreatic ductal adenocarcinoma growth and poor prognosis
Experimental and Molecular Pathology
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