Retraction: MiR-525-5p inhibits diffuse large B cell lymphoma progression via the Myd88 /NF-κB signaling pathway
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- Subject Areas
- Biochemistry, Cell Biology, Hematology, Oncology
- Keywords
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- © 2024 PeerJ Editorial Office
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- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
- Cite this article
- 2024. Retraction: MiR-525-5p inhibits diffuse large B cell lymphoma progression via the Myd88 /NF-κB signaling pathway. PeerJ 12:e16388/retraction https://doi.org/10.7717/peerj.16388/retraction
Retraction: Guo X, Zhang J, Zeng J, Guo Y, Zhao L. 2023. MiR-525-5p inhibits diffuse large B cell lymphoma progression via the Myd88/NF-κB signaling pathway. PeerJ 11:e16388 https://doi.org/10.7717/peerj.16388
After concerns were raised by a reader, an investigation by PeerJ has confirmed that:
A) the U2932 cell line reportedly used in this work has a small and round morphology, with cells growing singly and in clusters in suspension. However, photographs in figs. 4C and 5C show typical epithelial cell morphology suggesting the use of a contaminated cell line.
B) The protocols detailed in the Methods section for the Transwell assays do not include any modification to ensure that U2932 cells (which are a suspended cell line) would not be washed away when removing the culture medium. Therefore, even if U2932 cells had been present, they could not have been detected by this method.
The authors have been made aware of these issues, and confirmed that the maintenance conditions of their cells were conducive to inadvertent contamination. In agreement with the authors, the Publisher has therefore taken the decision to retract this article.
PeerJ Editorial Office. 2024. Retraction: MiR-525-5p inhibits diffuse large B cell lymphoma progression via the Myd88 /NF-κB signaling pathway. PeerJ 12:e16388/retraction https://doi.org/10.7717/peerj.16388/retraction.