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2026
Therapeutic effects of Lactobacillus rhamnosus, thymol and their combination against neurotoxicity in propionic acid (PA)-induced autistic rats: insights into the role of the Nrf2/HO-1, Wnt3/β-catenin/GSK3β BDNF/p-TrkB/CREB, pI3K/Akt/mTOR, AMPK/SIRT-1, and PERK/CHOP/Bcl-2 pathways
Frontiers in Pharmacology
Hoda A. Salem, Nermin I. Rizk, Moustafa H. AbdelSalam, Rehab Ahmed, Hebatallah Husseini Atteia, Ahmed M. E. Hamdan, Areej A. Alghamdi, Manar A. Alghusn, Renad A. Alatawi, Rawan A. Atallah, Maryam M. Alfuhaymani, Hatun A. Alqahtani, Karema Abu-Elfotuh
2025
Therapeutic effect of bismuth subsalicylate in a propionic acid–induced autism model
Naunyn-Schmiedeberg's Archives of Pharmacology
Kubilay Doğan Kılıç, Burak Çakar, Yiğit Uyanıkgil, Lora Koenhemsi, Berzah Güneş, Ebru Eroğlu, Oytun Erbaş
2025
‌Dual-target hUCMSCs/EVs therapy for autism spectrum disorder: remodeling gut microbiota and modulating neuroimmune crosstalk in a valproic acid-induced C57BL/6 mice model
Stem Cell Research & Therapy
Caixia Wu, Xianjie Li, Xiaoya Yang, Han Wang, Guanzhen Lin, Zhaoming Liu
2025
Gut microbiota remodeling exacerbates neuroinflammation and cognitive dysfunction via the microbiota-gut-brain axis in prenatal VPA-exposed C57BL/6 mice offspring
Frontiers in Immunology
Zhaoming Liu, Caixia Wu, Zhaojian Sun, Zuoxian Lin, Yirong Sun, Nouman Amjad, Muhammad Majid, Rajesh Basnet, Zhiyuan Li
2025
Prenatal Exposure to Lipopolysaccharide or Valproate Leads to Abnormal Accumulation of the NMDA Receptor Agonist D‐Aspartate in the Adolescent Rat Brain
Journal of Neurochemistry
Anna Di Maio, Isar Yahyavi, Valeria Buzzelli, Zoraide Motta, Fabrizio Ascone, Lorenza Putignani, Alessandro Usiello, Loredano Pollegioni, Viviana Trezza, Francesco Errico
2025
Cross-generational mechanisms of maternal gut microbiota in modulating offspring autism spectrum disorder risk: from the gut-brain axis to translational challenges in precision interventions
Frontiers in Aging Neuroscience
Dashuang Zhang, Min Zhou, Yudan Qiu, Hong Xu, Hanmin Liu, Yang Liu, Liang Xie