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2025
Role of Bcl-2 family anti-apoptosis inhibition in overcoming therapeutic resistance in prostate cancer: A systematic review
Critical Reviews in Oncology/Hematology
2025
A Critical Review on BH3 Mimetic Drugs and the Treatment of Cancer‐Associated Thrombosis (CAT): A Proposed Design for a Drug Delivery System Capable of Simultaneously Targeting Tumor Cells and Activated Platelets
Cancer Medicine
2025
Unveiling the potential targets and mechanisms of DEHP/BPA exposure on PCOS: insights from network toxicology and molecular docking
Journal of Ovarian Research
2023
IN SILICO STUDY OF THE SYNERGISTIC INTERACTION OF 5-FLUOROURACIL AND CURCUMIN ANALOGUES AS INHIBITORS OF B-CELL LYMPHOMA 2 PROTEIN
International Journal of Applied Pharmaceutics
2023
Protein Levels of Anti-Apoptotic Mcl-1 and the Deubiquitinase USP9x Are Cooperatively Upregulated during Prostate Cancer Progression and Limit Response of Prostate Cancer Cells to Radiotherapy
Cancers
2022
Mechanisms of cancer cell death induction by paclitaxel: an updated review
Apoptosis
2022
Repurposing BCL-2 and Jak 1/2 inhibitors: Cure and treatment of HIV-1 and other viral infections
Frontiers in Immunology
2022
Novel BH4-BCL-2 Domain Antagonists Induce BCL-2-Mediated Apoptosis in Triple-Negative Breast Cancer
Cancers
2021
Dual Akt and Bcl-2 inhibition induces cell-type specific modulation of apoptotic and autophagic signaling in castration resistant prostate cancer cell lines
Molecular Biology Reports
2021
Mechanisms of docetaxel resistance in prostate cancer: The key role played by miRNAs
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
2021
Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer
Cancers
2021
Novel Therapies in Myeloproliferative Neoplasms: Beyond JAK Inhibitor Monotherapy
Journal of Immunotherapy and Precision Oncology
2020
Mechanisms of Taxane Resistance
Cancers
2020
Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice
Toxicological Sciences
2020
Peptidomimetics: A Synthetic Tool for Inhibiting Protein–Protein Interactions in Cancer
International Journal of Peptide Research and Therapeutics
2020
AT101 [(-)-Gossypol] Selectively Inhibits MCL1 and Sensitizes Carcinoma to BH3 Mimetics by Inducing and Stabilizing NOXA
Cancers
2019
ABT-737 and erufosine combination against castration-resistant prostate cancer
Anti-Cancer Drugs
2019
Exploring Proteomic Drug Targets, Therapeutic Strategies and Protein - Protein Interactions in Cancer: Mechanistic View
Current Cancer Drug Targets
2019
Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability
Cell Death & Disease
2019
Regulating the BCL2 Family to Improve Sensitivity to Microtubule Targeting Agents
Cells
2018
Synergistic cytotoxicity of a prostate cancer-specific immunotoxin in combination with the BH3 mimetic ABT-737
Cancer Immunology, Immunotherapy
2018
Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin
Oncotarget
2018
Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells
Scientific Reports
2017
BH3 Mimetics for the Treatment of Prostate Cancer
Frontiers in Pharmacology
2017
CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer
Oncotarget
2017
Implications of Bcl-2 and its interplay with other molecules and signaling pathways in prostate cancer progression
Expert Opinion on Therapeutic Targets
2017
Neural Stem Cell Transplantation Is Associated with Inhibition of Apoptosis, Bcl-xL Upregulation, and Recovery of Neurological Function in a Rat Model of Traumatic Brain Injury
Cell Transplantation
2016
Enhanced anticancer effect of ABT-737 in combination with naringenin on gastric cancer cells
Experimental and Therapeutic Medicine
2016
Physiological and Pharmacological Control of BAK, BAX, and Beyond
Trends in Cell Biology
2016
Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy
British Journal of Cancer
2016
Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53
Cell Cycle
2016
Improving Taxane-Based Chemotherapy in Castration-Resistant Prostate Cancer
Trends in Pharmacological Sciences
2015
Antitumor activity of paclitaxel is significantly enhanced by a novel proapoptotic agent in non–small cell lung cancer
Journal of Surgical Research
2015
Combining Paclitaxel with ABT-263 Has a Synergistic Effect on Paclitaxel Resistant Prostate Cancer Cells
PLOS ONE
2015
Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy
Oncotarget
2015
Bcl-2 family of proteins as drug targets for cancer chemotherapy: the long way of BH3 mimetics from bench to bedside
Current Opinion in Pharmacology
2015
Bcl-xL inhibition by molecular-targeting drugs sensitizes human pancreatic cancer cells to TRAIL
Oncotarget
2015
Broad targeting of resistance to apoptosis in cancer
Seminars in Cancer Biology
2015
Atelocollagen-Mediated Intravenous siRNA Delivery Specific to Tumor Tissues Orthotopically Xenografted in Prostates of Nude Mice and Its Anticancer Effects
Nucleic Acid Therapeutics
2015
Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage
Oncoscience
2014
Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition
Oncotarget
2014
Gonadotropin-Releasing Hormone Agonists Sensitize, and Resensitize, Prostate Cancer Cells to Docetaxel in a p53-Dependent Manner
PLoS ONE
2014
Synergistic Antitumor Activities of Docetaxel and Octreotide Associated with Apoptotic-Upregulation in Castration-Resistant Prostate Cancer
PLoS ONE
2014
Protein kinase C in the wood frog,Rana sylvatica: reassessing the tissue-specific regulation of PKC isozymes during freezing
PeerJ
2014
Rapid screening of protein–protein interaction inhibitors using the protease exclusion assay
Biosensors and Bioelectronics
2014
Emodin enhances ATRA-induced differentiation and induces apoptosis in acute myeloid leukemia cells
International Journal of Oncology