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2025
Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk
PLOS Pathogens
2025
Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae
Nature Communications
2025
Changes in Soil Microbial Community Structure and Assembly Process Under Different Forest Restoration Strategies in Cold Temperate Forests of Northeastern China
Microorganisms
2025
CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa
Nature Communications
2025
Make-or-break prime editing for genome engineering in Streptococcus pneumoniae
Nature Communications
2025
A quantitative intracellular peptide-binding assay reveals recognition determinants and context dependence of short linear motifs
Journal of Biological Chemistry
2025
High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants
Nature Communications
2025
CRISPRi-ART enables functional genomics of diverse bacteriophages using RNA-binding dCas13d
Nature Microbiology
2025
The virulence regulator CovR boosts CRISPR-Cas9 immunity in Group B Streptococcus
Nature Communications
2024
Genome-wide CRISPRi screens for high-throughput fitness quantification and identification of determinants for dalbavancin susceptibility in Staphylococcus aureus
mSystems
2024
High-Speed Biomedical Imaging and Spectroscopy IX
2024
Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase
Cell Reports
2024
A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection
Cell Host & Microbe
2024
CRISPRi functional genomics in bacteria and its application to medical and industrial research
Microbiology and Molecular Biology Reviews
2024
qTAG: an adaptable plasmid scaffold for CRISPR-based endogenous tagging
The EMBO Journal
2023
Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence
PLOS Biology
2023
Is AI essential? Examining the need for deep learning in image-activated sorting of Saccharomyces cerevisiae
Lab on a Chip
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