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2025
Activating NEDD4L suppresses EGFR-driven lung adenocarcinoma growth via facilitating EGFR proteasomal degradation
Journal of Experimental & Clinical Cancer Research
2025
NEDD4L inhibits epithelial‐mesenchymal transition in gastric cancer by mediating BICC1 ubiquitination
The Kaohsiung Journal of Medical Sciences
2025
Key subunits of γ-secretase complex and breast cancer progression: biological function, regulation mode and therapeutic potential
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
2024
Targeting Nrf2 signaling pathways in the role of bladder cancer: From signal network to targeted therapy
Biomedicine & Pharmacotherapy
2024
E3 Ubiquitin Ligase NEDD4L Negatively Regulates Skin Tumorigenesis by Inhibiting IL-6/GP130 Signaling Pathway
Journal of Investigative Dermatology
2024
Advances of E3 ligases in lung cancer
Biochemistry and Biophysics Reports
2024
Multi-Omics Characterization of E3 Regulatory Patterns in Different Cancer Types
International Journal of Molecular Sciences
2024
Secretase promotes AD progression: simultaneously cleave Notch and APP
Frontiers in Aging Neuroscience
2023
NEDD4L in human tumors: regulatory mechanisms and dual effects on anti-tumor and pro-tumor
Frontiers in Pharmacology
2023
Combining single-cell RNA sequencing data and transcriptomic data to unravel potential mechanisms and signature genes of the progression of idiopathic pulmonary fibrosis to lung adenocarcinoma and predict therapeutic agents
Functional & Integrative Genomics
2023
NEDD4L inhibits migration, invasion, cisplatin resistance and promotes apoptosis of bladder cancer cells by inactivating the p62/Keap1/Nrf2 pathway
Environmental Toxicology
2023
NEDD4 E3 ubiquitin ligases: Promising biomarkers and therapeutic targets for cancer
Biochemical Pharmacology
2023
14-3-3σ-NEDD4L axis promotes ubiquitination and degradation of HIF-1α in colorectal cancer
Cell Reports