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2026
Comprehensive Toxicology
2025
LAMP1 as a Target for PET Imaging in Adenocarcinoma Xenograft Models
Pharmaceuticals
2024
Life cell imaging of amiodarone sequestration into lamellar bodies of alveolar type II cells
Toxicology in Vitro
2022
Failed Repurposing of Lysosomotropic Drugs for COVID-19 Treatment or Prevention
Drugs and Drug Candidates
2021
Oleate-induced aggregation of LC3 at the trans-Golgi network is linked to a protein trafficking blockade
Cell Death & Differentiation
2021
Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia
Nature Communications
2020
Uptake Study in Lysosome-Enriched Fraction: Critical Involvement of Lysosomal Trapping in Quinacrine Uptake but Not Fluorescence-Labeled Verapamil Transport at Blood-Retinal Barrier
Pharmaceutics
2020
Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines
Oncotarget
2020
Repurposing Quinacrine for Treatment of Malignant Mesothelioma: In-Vitro Therapeutic and Mechanistic Evaluation
International Journal of Molecular Sciences
2019
Ultraspecific live imaging of the dynamics of zebrafish neutrophil granules by a histopermeable fluorogenic benzochalcone probe
Chemical Science
2019
Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma
Oncotarget
2018
Bifunctional fusion proteins containing the sequence of the bradykinin homologue maximakinin: activities at the rat bradykinin B2 receptor
Canadian Journal of Physiology and Pharmacology
2018
Quinacrine enhances temozolomide cytotoxicity in temozolomide-sensitive and -resistant glioblastoma cells
Glioma
2018
Comprehensive Toxicology
2018
The autophagy inhibitor spautin-1, either alone or combined with doxorubicin, decreases cell survival and colony formation in canine appendicular osteosarcoma cells
PLOS ONE
2017
New insights into the intracellular distribution pattern of cationic amphiphilic drugs
Scientific Reports
2017
Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity
Journal of Applied Toxicology
2016
Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation
Toxicology and Applied Pharmacology
2016
Clofazimine Biocrystal Accumulation in Macrophages Upregulates Interleukin 1 Receptor Antagonist Production To Induce a Systemic Anti-Inflammatory State
Antimicrobial Agents and Chemotherapy
2016
HIV-1 Tat Promotes Lysosomal Exocytosis in Astrocytes and Contributes to Astrocyte-mediated Tat Neurotoxicity
Journal of Biological Chemistry