Review History


To increase transparency, PeerJ operates a system of 'optional signed reviews and history'. This takes two forms: (1) peer reviewers are encouraged, but not required, to provide their names (if they do so, then their profile page records the articles they have reviewed), and (2) authors are given the option of reproducing their entire peer review history alongside their published article (in which case the complete peer review process is provided, including revisions, rebuttal letters and editor decision letters).

New to public reviews? Learn more about optional signed reviews and how to write a better rebuttal letter.

Summary

  • The initial submission of this article was received on June 27th, 2013 and was peer-reviewed by 2 reviewers and the Academic Editor.
  • The article was Accepted by the Academic Editor on July 25th, 2013.

Version 0.1 (accepted)

· · Academic Editor

Accept

Dear Dr. Niggli,
I am pleased to report that the reviewers of your manuscript were quite favorable and supported publishing the manuscript as it is. Therefore, we are happy to accept your manuscript for publication.
Sincerely,
Martin Poenie

Reviewer 1 ·

Basic reporting

The article meets all of the standards for publication in PeerJ

Experimental design

The article meets all of the standards for publication in PeerJ

Validity of the findings

The article meets all of the standards for publication in PeerJ

Comments for the author

This is an interesting and useful addition to the literature

Reviewer 2 ·

Basic reporting

No comments.

Experimental design

No comments.

Validity of the findings

No comments.

Comments for the author

Mathis et al investigated the molecular determinants of PIPKIγ90 localization at the T cell uropod and how uropod formation is controlled by this isoform. Using overexpression of PIPKIγ90 variants in WT T cells and experiments in PIPKIγ90-null cells they report that the C-terminal 26 amino acids of the protein are required for uropod localization and further propose that recruitment of PIPKIγ90 to the uropod requires flotillins.

This is a well-written and well-presented manuscript on an interesting topic. The work is well done and well controlled. I recommend publication in PeerJ as is.

All text and materials provided via this peer-review history page are made available under a Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.