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Dear Dr. Niggli,
I am pleased to report that the reviewers of your manuscript were quite favorable and supported publishing the manuscript as it is. Therefore, we are happy to accept your manuscript for publication.
Sincerely,
Martin Poenie
The article meets all of the standards for publication in PeerJ
The article meets all of the standards for publication in PeerJ
The article meets all of the standards for publication in PeerJ
This is an interesting and useful addition to the literature
No comments.
No comments.
No comments.
Mathis et al investigated the molecular determinants of PIPKIγ90 localization at the T cell uropod and how uropod formation is controlled by this isoform. Using overexpression of PIPKIγ90 variants in WT T cells and experiments in PIPKIγ90-null cells they report that the C-terminal 26 amino acids of the protein are required for uropod localization and further propose that recruitment of PIPKIγ90 to the uropod requires flotillins.
This is a well-written and well-presented manuscript on an interesting topic. The work is well done and well controlled. I recommend publication in PeerJ as is.
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