Contributions by role
Contributions by subject area
Eduardo Cienfuegos-Pecina
Summary
My main interest is to understand the role of oxygen metabolism in the physiopathology of ischemia-reperfusion injury, chronic liver disease, and cancer. Alterations in oxygen metabolism induced by the up or downregulation of the Hypoxia-Inducible Factors have been demonstrated to either drive the course of these pathologies or be a therapeutic strategy, as they are highly involved with the action of proto-oncogenes and tumor suppressor genes. Untargeted analytical techniques, such as NMR-based metabolomics, allow us to characterize the effect of treatments regulating the oxygen metabolism pathways and to identify secondary pathways affected by the disease or the treatment itself.
Biochemistry Bioorganic Chemistry Gastroenterology & Hepatology Nephrology NMR Spectroscopy Synthetic Organic Chemistry