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2025
Ursodeoxycholic acid prompts glycolytic dominance, reductive stress and epithelial-to-mesenchymal transition in ovarian cancer cells through NRF2 activation
Cell Death Discovery
2025
Diet and the microbiome as mediators of prostate cancer risk, progression, and therapy response
Urologic Oncology: Seminars and Original Investigations
2025
Insights into the gut microbiome-metabolite dynamics in breast cancer
Gut Microbes Reports
2025
The gut microbiome and cancer: from tumorigenesis to therapy
Nature Metabolism
2025
Docetaxel-conjugated bile acid-derived nanomicelles can inhibit tumour progression with reduced toxicity
Nanoscale Advances
2024
Facial Amphiphile-Modified Lipids Highly Sensitize Liposomes toward Secretory Phospholipase A2
Molecular Pharmaceutics
2024
Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets
Signal Transduction and Targeted Therapy
2024
Lithocholic acid-based oligomers as drug delivery candidates targeting model of lipid raft
Biochimica et Biophysica Acta (BBA) - Biomembranes
2024
The anticancer activity of bile acids in drug discovery and development
Frontiers in Pharmacology
2024
Interplay between Bile Acids and Intestinal Microbiota: Regulatory Mechanisms and Therapeutic Potential for Infections
Pathogens
2024
Microbiome and Prostate Cancer: Emerging Diagnostic and Therapeutic Opportunities
Pharmaceuticals
2023
Metabolomic epidemiology offers insights into disease aetiology
Nature Metabolism
2023
Natural products derived from medicinal plants and microbes might act as a game-changer in breast cancer: a comprehensive review of preclinical and clinical studies
Critical Reviews in Food Science and Nutrition
2023
Gut microbiota in cancer: insights on microbial metabolites and therapeutic strategies
Medical Oncology
2023
The tremendous clinical potential of the microbiota in the treatment of breast cancer: the next frontier
Journal of Cancer Research and Clinical Oncology
2023
Irradiation-Induced Intestinal Injury is Associated With Disorders of Bile Acids Metabolism
International Journal of Radiation Oncology*Biology*Physics
2022
Mechanism of Bile Acid-Induced Programmed Cell Death and Drug Discovery against Cancer: A Review
International Journal of Molecular Sciences
2022
Comprehensive Gut Microbiota
2022
The role of key gut microbial metabolites in the development and treatment of cancer
Gut Microbes
2022
The role of bile acids in carcinogenesis
Cellular and Molecular Life Sciences
2022
In vitro protoscolicidal effects of lithocholic acid on protoscoleces of Echinococcus granulosus and its mechanism
Experimental Parasitology
2022
Mode of Actions of Bile Acids in Avoidance of Colorectal Cancer Development; and their Therapeutic Applications in Cancers - A Narrative Review
Journal of Pharmacy and Nutrition Sciences
2022
Late-Stage Glioma Is Associated with Deleterious Alteration of Gut Bacterial Metabolites in Mice
Metabolites
2022
Lithocholic acid inhibits gallbladder cancer proliferation through interfering glutaminase-mediated glutamine metabolism
Biochemical Pharmacology
2022
Do Bacteria Provide an Alternative to Cancer Treatment and What Role Does Lactic Acid Bacteria Play?
Microorganisms
2022
Impact of intestinal dysbiosis on breast cancer metastasis and progression
Frontiers in Oncology
2021
Canine Genetics, Health and Medicine
2021
Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
Cancers
2021
Anticancer Effects of Ursi Fel Extract and Its Active Compound, Ursodeoxycholic Acid, in FRO Anaplastic Thyroid Cancer Cells
Molecules
2021
Physiology and Physical Chemistry of Bile Acids
International Journal of Molecular Sciences
2021
The involvement of oncobiosis and bacterial metabolite signaling in metastasis formation in breast cancer
Cancer and Metastasis Reviews
2020
Synthesis of New Cisplatin Derivatives from Bile Acids
Molecules
2020
Synthesis of novel dimeric compounds containing triazole using click method and their selective antiproliferative and proapoptotic potential via mitochondrial apoptosis signaling
Medicinal Chemistry Research
2020
Oncobiosis and Microbial Metabolite Signaling in Pancreatic Adenocarcinoma
Cancers
2020
Sorafenib loaded pluronic F127-lithocholic acid micelles for prostate cancer therapy: Formulation, optimization, and in vitro evaluation against LNCaP cells
International Journal of Polymeric Materials and Polymeric Biomaterials
2020
Updates in bile acid-bioactive molecule conjugates and their applications
Steroids
2020
Lithocholic bile acid induces apoptosis in human nephroblastoma cells: a non-selective treatment option
Scientific Reports
2019
Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells
The Journal of Steroid Biochemistry and Molecular Biology
2019
Microbiome—Microbial Metabolome—Cancer Cell Interactions in Breast Cancer—Familiar, but Unexplored
Cells
2019
Computational study of new 1,2,3-triazole derivative of lithocholic acid: Structural aspects, non-linear optical properties and molecular docking studies as potential PTP 1B enzyme inhibitor
Computational Biology and Chemistry
2019
Lithocholic Acid, a Metabolite of the Microbiome, Increases Oxidative Stress in Breast Cancer
Cancers
2018
Clickable conjugates of bile acids and nucleosides: Synthesis, characterization, in vitro anticancer and antituberculosis studies
Steroids
2018
LXRs, SHP, and FXR in Prostate Cancer: Enemies or Ménage à Quatre With AR?
Nuclear Receptor Signaling
2018
Programmed ‘triple-mode’ anti-tumor therapy: Improving peritoneal retention, tumor penetration and activatable drug release properties for effective inhibition of peritoneal carcinomatosis
Biomaterials
2018
Lithocholic bile acid inhibits lipogenesis and induces apoptosis in breast cancer cells
Cellular Oncology
2018
Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness
Biochimica et Biophysica Acta (BBA) - Bioenergetics
2018
Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions
Oncotarget
2018
Synthesis of a cisplatin derivative from lithocholic acid
Tetrahedron
2018
Lithocholic Acid Improves the Survival of Drosophila Melanogaster
Molecular Nutrition & Food Research
2017
Rethinking the bile acid/gut microbiome axis in cancer
Oncotarget
2017
Bile Acids and Cancer: Direct and Environmental-Dependent Effects
Annals of Hepatology
2017
Combination therapy of paclitaxel and cyclopamine polymer-drug conjugates to treat advanced prostate cancer
Nanomedicine: Nanotechnology, Biology and Medicine
2017
The synthesis and antitumor activity of lithocholic acid and its derivatives
Steroids
2017
Ursodeoxycholic Acid Induces Death Receptor-mediated Apoptosis in Prostate Cancer Cells
Journal of Cancer Prevention
2017
Bile acids and their oxo derivatives: Potential inhibitors of carbonic anhydrase I and II, androgen receptor antagonists and CYP3A4 substrates
Biomedical Chromatography
2017
Combination therapy with doxorubicin-loaded galactosylated poly(ethyleneglycol)-lithocholic acid to suppress the tumor growth in an orthotopic mouse model of liver cancer
Biomaterials
2016
Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells
PeerJ
2016
Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes
Oncotarget
2016
Genome-wide methylation analysis of retrocopy-associated CpG islands and their genomic environment
Epigenetics
2016
Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms
Frontiers in Genetics
2016
A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis
Oncotarget
2016
Protoscolicidal effects of chenodeoxycholic acid on protoscoleces of Echinococcus granulosus
Experimental Parasitology
2016
Low-frequency ultrasound-mediated microvessel disruption combined with docetaxel to treat prostate carcinoma xenografts in nude mice: A novel type of chemoembolization
Oncology Letters
2016
Synthesis, characterization and biological evaluation of bile acid-aromatic/heteroaromatic amides linked via amino acids as anti-cancer agents
Steroids
2015
Galactosylated Poly(Ethyleneglycol)‐Lithocholic Acid Selectively Kills Hepatoma Cells, While Sparing Normal Liver Cells
Macromolecular Bioscience
2015
When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?
Current Pharmacology Reports
2015
Optimization of low-frequency low-intensity ultrasound-mediated microvessel disruption on prostate cancer xenografts in nude mice using an orthogonal experimental design
Oncology Letters
2015
Low-frequency and low-intensity ultrasound-mediated microvessel disruption enhance the effects of radiofrequency ablation on prostate cancer xenografts in nude mice
Molecular Medicine Reports
2015
Absorption-Enhancing Effects of Bile Salts
Molecules
2015
Cross‐talk between bile acids and gastrointestinal tract for progression and development of cancer and its therapeutic implications
IUBMB Life
2015
The role of bile acids in reducing the metabolic complications of obesity after bariatric surgery: a systematic review
International Journal of Obesity
2014
Protein kinase C in the wood frog,Rana sylvatica: reassessing the tissue-specific regulation of PKC isozymes during freezing
PeerJ
2014
EsophagealHelicobacter pyloricolonization aggravates esophageal injury caused by reflux
World Journal of Gastroenterology
2014
Nanoways to overcome docetaxel resistance in prostate cancer
Drug Resistance Updates
2014
Mechanisms Underlying the Anti-Aging and Anti-Tumor Effects of Lithocholic Bile Acid
International Journal of Molecular Sciences
2014
Feasibility of Detecting Prostate Cancer by Ultraperformance Liquid Chromatography–Mass Spectrometry Serum Metabolomics
Journal of Proteome Research
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