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2025
Design, synthesis and anti-pneumonic activity evaluation of shikonin ester derivatives
Bioorganic & Medicinal Chemistry Letters
2025
Shikonin a potent phytotherapeutic: a comprehensive review on metabolic reprogramming to overcome drug resistance in cancer
Molecular Biology Reports
2025
Ethnopharmacology, Geographic Distribution, Major Chemical Constituents, and Pharmacological Effects of the Traditional Chinese Medicinal Herb Arnebia euchroma
Natural Product Communications
2025
Elucidating the Therapeutic Mechanisms of Dendrobium loddigesii in Gastric Mucosal Injury: An Integrated Approach Combining Serum Metabolomics and Network Pharmacology
Biomedical Chromatography
2024
Shikonin ameliorated LPS-induced acute lung injury in mice via modulating MCU-mediated mitochondrial Ca2+ and macrophage polarization
Phytomedicine
2024
Bioavailability and Pharmacological Properties of Shikonin‐ A Phytocompound from Lithospermum Erythrorhizon
ChemistrySelect
2024
Research Progress on Mechanism of Shikonin in Treatment of Colitis
Journal of Contemporary Medical Practice
2024
Shikonin ameliorates depressive- and anxiogenic-like behaviors in rats via the suppression of inflammation in the hippocampus
Neuroscience Letters
2024
Shikonin induces the apoptosis and pyroptosis of EGFR-T790M-mutant drug-resistant non-small cell lung cancer cells via the degradation of cyclooxygenase-2
European Journal of Medical Research
2024
Shikonin delivery nano system based on calcium alginate for targeted therapy of inflammatory bowel disease by modulating macrophage polarization
Journal of Drug Delivery Science and Technology
2024
Shikonin potentiates skin wound healing in Sprague–Dawley rats by stimulating fibroblast and endothelial cell proliferation and angiogenesis
The Journal of Gene Medicine
2024
So Shiho Tang Reduces Inflammation in Lipopolysaccharide-Induced RAW 264.7 Macrophages and Dextran Sodium Sulfate-Induced Colitis Mice
Biomolecules
2023
Unveiling the Potentiality of Shikonin Derivatives Inhibiting SARS-CoV-2 Main Protease by Molecular Dynamic Simulation Studies
International Journal of Molecular Sciences
2023
Progress on Regulation of NLRP3 Inflammasome by Chinese Medicine in Treatment of Ulcerative Colitis
Chinese Journal of Integrative Medicine
2023
Treatment Effects of Natural Products on Inflammatory Bowel Disease In Vivo and Their Mechanisms: Based on Animal Experiments
Nutrients
2023
Recent advances in shikonin for the treatment of immune-related diseases: Anti-inflammatory and immunomodulatory mechanisms
Biomedicine & Pharmacotherapy
2022
Shikonin, a naphthalene ingredient: Therapeutic actions, pharmacokinetics, toxicology, clinical trials and pharmaceutical researches
Phytomedicine
2022
Shikonin ameliorated mice colitis by inhibiting dimerization and tetramerization of PKM2 in macrophages
Frontiers in Pharmacology
2022
Review of Shikonin and Derivatives: Isolation, Chemistry, Biosynthesis, Pharmacology and Toxicology
Frontiers in Pharmacology
2022
Combined Shikonin-Loaded MPEG-PCL Micelles Inhibits Effective Transition of Endothelial-to-Mesenchymal Cells
International Journal of Nanomedicine
2022
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer
International Immunopharmacology
2022
Potential activity of Traditional Chinese Medicine against Ulcerative colitis: A review
Journal of Ethnopharmacology
2022
“Shikonin inhibits microglia activation and reduces CFA-induced mechanical hyperalgesia in an animal model of pain”
Biomedicine & Pharmacotherapy
2022
Research Progress on Structure and Anti-Gynecological Malignant Tumor of Shikonin
Frontiers in Chemistry
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