Peer-reviewed Articles

We propose here a working unit for teaching basic concepts of structural bioinformatics and evolution through the example of a wooden snake puzzle, strikingly similar to toy models widely used in the literature of protein folding. In our experience, developed at...

["Bioinformatics","Computational Biology","Computer Education","Scientific Computing and Simulation"]
doi:10.7717/peerj-cs.100
30 downloads
633 views

Corvids (birds in the crow family) are hypothesised to have a general cognitive tool-kit because they show a wide range of transferrable skills across social, physical and temporal tasks, despite differences in socioecology. However, it is unknown whether relatively...

["Animal Behavior","Zoology"]
doi:10.7717/peerj.2746
95 downloads
214 views

Vegetation response to nutrient addition can vary across space, yet studies that explicitly incorporate spatial pattern into experimental approaches are rare. To explore whether there are unique spatial scales (grains) at which grass response to nutrients and herbivory...

["Agricultural Science","Conservation Biology","Ecology","Ecosystem Science","Plant Science"]
doi:10.7717/peerj.2745
20 downloads
151 views

Tissue microarrays are commonly used in modern pathology for cancer tissue evaluation, as it is a very potent technique. Tissue microarray slides are often scanned to perform computer-aided histopathological analysis of the tissue cores. For processing the image,...

["Computational Biology","Pathology","Histology"]
doi:10.7717/peerj.2741
28 downloads
147 views

Drosophila embryogenesis has proven to be an extremely powerful system for developmental gene discovery and characterization. We isolated five new EMS-induced alleles that do not complement the l(3R)5G83 lethal line isolated in the Nüsslein-Volhard and Wieschaus...

["Cell Biology","Developmental Biology","Genetics"]
doi:10.7717/peerj.2731
31 downloads
170 views

The effective management of invasive species requires detailed understanding of the invader’s life history. This information is essential for modeling population growth and predicting rates of expansion, quantifying ecological impacts and assessing the efficacy...

["Aquaculture, Fisheries and Fish Science","Conservation Biology","Ecology","Marine Biology"]
doi:10.7717/peerj.2730
22 downloads
126 views

The design of experiments and the validation of the results achieved with them are vital in any research study. This paper focuses on the use of different Machine Learning approaches for regression tasks in the field of Computational Intelligence and especially...

["Bioinformatics","Computational Biology","Molecular Biology","Statistics","Computational Science"]
doi:10.7717/peerj.2721
27 downloads
123 views

Background Age remains a significant and unmodifiable risk factor for cardiovascular diseases, and an increasing number of patients older than 80 years of age undergo Coronary Artery Bypass Grafting (CABG). Old age is also an independent risk factor for postoperative...

["Cardiology","Epidemiology","Geriatrics","Nursing","Surgery and Surgical Specialties"]
doi:10.7717/peerj.2667
51 downloads
604 views

3D printers that build objects using extruded thermoplastic are quickly becoming commonplace tools in laboratories. We demonstrate that with appropriate handling, these devices are capable of producing sterile components from a non-sterile feedstock of thermoplastic...

["Bioengineering","Biotechnology","Microbiology"]
doi:10.7717/peerj.2661
22 downloads
154 views

The ontogenesis of the nasal cavity has been described in many mammalian species. The situation is different with reptiles, despite the fact that they have become relatively common as pets. In this study we focused on the ontogenesis of the olfactory epithelium,...

["Biodiversity","Veterinary Medicine","Zoology","Histology"]
doi:10.7717/peerj.2561
34 downloads
210 views

Streptococcus pneumoniae is a pathogen that causes serious invasive infections, such as septicemia, meningitis and pneumonia in addition to mild upper respiratory tract infections. Protection from pneumococcal diseases is thought to be mediated mainly by serotype-specific...

["Immunology","Infectious Diseases"]
doi:10.7717/peerj.2737
48 downloads
246 views

Brain perfusion is of key importance to assess brain function. Modern CT scanners can acquire perfusion maps of the cerebral parenchyma in vivo at submillimeter resolution. These perfusion maps give insights into the hemodynamics of the cerebral parenchyma and...

["Radiology and Medical Imaging","Neurology","Computational Science"]
doi:10.7717/peerj.2683
36 downloads
181 views

Background Shugoshins (SGOs) are proteins that protect cohesins located at the centromeres of sister chromatids from their early cleavage during mitosis and meiosis in plants, fungi, and animals. Their function is to prevent premature sister-chromatid disjunction...

["Bioinformatics","Cell Biology","Computational Biology","Evolutionary Studies"]
doi:10.7717/peerj.2736
40 downloads
225 views

The giant river prawn (Macrobrachium rosenbergii) is one of the most farmed freshwater crustaceans in the world. Its global production has been stalling in the past decade due to the inconsistent quality of broodstock and hatchery-produced seeds. A better understanding...

["Agricultural Science","Aquaculture, Fisheries and Fish Science"]
doi:10.7717/peerj.2735
43 downloads
218 views

Complete chloroplast genome sequences have been very useful for understanding phylogenetic relationships in angiosperms at the family level and above, but there are currently large gaps in coverage. We report the chloroplast genome for Helwingia himalaica, the...

["Genomics","Plant Science"]
doi:10.7717/peerj.2734

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