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Vladimir Uversky
Gold Contributor
40,390 Points

Contributions by role

Author 1,485
Preprint Author 175
Reviewer 85
Editor 38,645

Contributions by subject area

Bioinformatics
Computational Biology
Biochemistry
Biophysics
Microbiology
Molecular Biology
Infectious Diseases
Virology
COVID-19
Biotechnology
Cell Biology
Diabetes and Endocrinology
Oncology
Emergency and Critical Care
Medical Genetics
Genomics
Pharmacology
Computational Science
Histology
Hematology
Public Health
Gastroenterology and Hepatology
Developmental Biology
Gynecology and Obstetrics
Dermatology
Agricultural Science
Data Science
Entomology
Plant Science
Geriatrics
Food Science and Technology
Metabolic Sciences
Immunology
Synthetic Biology
Women's Health
Aquaculture, Fisheries and Fish Science
Otorhinolaryngology
Evolutionary Studies
Toxicology
Zoology
Biodiversity
Ecology
Genetics
Marine Biology
Cardiology
Data Mining and Machine Learning
Urology
Neurology
Mathematical Biology
Databases
Neuroscience
Parasitology
Drugs and Devices
Animal Behavior
Translational Medicine
Bioengineering
Veterinary Medicine
Nutrition
Pediatrics
Nephrology
Pathology
Ophthalmology
Evidence Based Medicine
Andrology
Respiratory Medicine
Radiology and Medical Imaging
Surgery and Surgical Specialties
Environmental Contamination and Remediation
Anesthesiology and Pain Management
Kinesiology
Orthopedics
Ecotoxicology
Dentistry
Algorithms and Analysis of Algorithms
Software Engineering
Visual Analytics
Forestry
Rheumatology
Environmental Impacts
Conservation Biology
Anthropology
Global Health
Epidemiology
Statistics
Environmental Health
Cognitive Disorders
Mycology
Anatomy and Physiology
Taxonomy
Population Biology
Biogeochemistry
Allergy and Clinical Immunology
Internal Medicine
Biosphere Interactions
Obesity
Soil Science
Aquatic and Marine Chemistry
Freshwater Biology
Embedded Computing
Real-Time and Embedded Systems
Gold Contributor

Vladimir N Uversky

PeerJ Editor, Author & Reviewer

Summary

Professor at the Department of Molecular Medicine of University of South Florida, College of Medicine, and Visiting Professor at Moscow Institute of Physics and Technology.
I received my B.S. and M.S. degrees in Physics from Leningrad State University in Russia in 1986, then, completed Ph.D. and Doctor of Sciences (D.Sc.) degrees in Physics and Mathematics (field of study - Biophysics) at the Moscow Institute of Physics and Technology (1991) and the Institute Experimental and Theoretical Biophysics of the Russian Academy of Sciences (1998), respectively. I spent early career working on protein folding at Institute of Protein Research and the Institute for Biological Instrumentation (Russia). In 1998, I moved to the University of California Santa Cruz to study protein folding, misfolding, protein conformation diseases, and protein intrinsic disorder phenomenon. In 2004, I was invited to join the Indiana University School of Medicine to primary work on the intrinsically disordered proteins. Since 2010, I am with USF, where I continue to study intrinsically disordered proteins and analyze protein folding and misfolding processes.
I have authored over 950 scientific publications. I am an editor of several scientific journals and edited a number of books and book series on protein structure, function, folding, and misfolding. Since 2014, I am included by the Thomson Reuters to the Clarivate list of Highly Cited Researchers™.

Biochemistry Bioinformatics Biophysics Computational Biology Molecular Biology

Editing Sections

Biochemistry, Biophysics and Molecular Biology

Editing Journals

PeerJ - the Journal of Life & Environmental Sciences

Past or current institution affiliations

University of South Florida

Work details

Professor

University of South Florida
Department of Molecular Medicine
Our scientific interests are broadly defined as everything related to protein folding, misfolding and non-folding. However, the passion is definitely the field of protein non-folding , which is related to the discovery of intrinsically disordered proteins (IDPs), analysis of their abundance in nature, characterization of their exceptional structural and functional plasticity, understanding of their vital roles in various biological processes, and establishing their involvement in the pathogenesis of multiple human diseases. These and related aspects of IDPs are analyzed by a combination of a wide spectrum of computational, bioinformatics, and experimental approaches of modern protein biophysics. Due to the high abundance of IDPs in various proteomes, the exceptional structural and functional plasticity of these proteins, and their intimate relations to the maladies' pathogenesis, it is almost impossible to find an area of protein science where IDPs would not play a noticeable role.

Websites

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  • ResearchGate
  • PubMed Search

PeerJ Contributions

  • Articles 11
  • Preprints 5
  • Edited 345
  • Reviewed 2
January 30, 2023
Exploring the mechanisms by which camel lactoferrin can kill Salmonella enterica serovar typhimurium and Shigella sonnei
Hussein A. Almehdar, Nawal Abd El-Baky, Ehab H. Mattar, Raed Albiheyri, Atif Bamagoos, Abdullah Aljaddawi, Vladimir N. Uversky, Elrashdy M. Redwan
https://doi.org/10.7717/peerj.14809
March 21, 2022
An issue of concern: unique truncated ORF8 protein variants of SARS-CoV-2
Sk. Sarif Hassan, Vaishnavi Kodakandla, Elrashdy M. Redwan, Kenneth Lundstrom, Pabitra Pal Choudhury, Tarek Mohamed Abd El-Aziz, Kazuo Takayama, Ramesh Kandimalla, Amos Lal, Ángel Serrano-Aroca, Gajendra Kumar Azad, Alaa A.A. Aljabali, Giorgio Palù, Gaurav Chauhan, Parise Adadi, Murtaza Tambuwala, Adam M. Brufsky, Wagner Baetas-da-Cruz, Debmalya Barh, Vasco Azevedo, Nikolas G. Bazan, Bruno Silva Andrade, Raner José Santana Silva, Vladimir N. Uversky
https://doi.org/10.7717/peerj.13136 PubMed 35341060
May 19, 2021
Chemical synthesis of peptidoglycan mimetic–disaccharide-tetrapeptide conjugate and its hydrolysis by bacteriophage T5, RB43 and RB49 L-alanyl-D-glutamate peptidases
Viatcheslav Azev, Alexey Chulin, Maxim Molchanov, Dmitry Prokhorov, Galina Mikoulinskaia, Vladimir N. Uversky, Viktor Kutyshenko
https://doi.org/10.7717/peerj.11480 PubMed 34055493
April 14, 2021
Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?
Ehab H. Mattar, Fatma Elrashdy, Hussein A. Almehdar, Vladimir N. Uversky, Elrashdy M. Redwan
https://doi.org/10.7717/peerj.11303 PubMed 33954061
June 22, 2016
Simple approach for ranking structure determining residues
Oscar D. Luna-Martínez, Abraham Vidal-Limón, Miryam I. Villalba-Velázquez, Rosalba Sánchez-Alcalá, Ramón Garduño-Juárez, Vladimir N. Uversky, Baltazar Becerril
https://doi.org/10.7717/peerj.2136 PubMed 27366642
April 18, 2016
Structure and stability of recombinant bovine odorant-binding protein: III. Peculiarities of the wild type bOBP unfolding in crowded milieu
Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, Konstantin K. Turoverov
https://doi.org/10.7717/peerj.1642 PubMed 27114858
April 18, 2016
Structure and stability of recombinant bovine odorant-binding protein: II. Unfolding of the monomeric forms
Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, Konstantin K. Turoverov
https://doi.org/10.7717/peerj.1574 PubMed 27114857
April 18, 2016
Structure and stability of recombinant bovine odorant-binding protein: I. Design and analysis of monomeric mutants
Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, Konstantin K. Turoverov
https://doi.org/10.7717/peerj.1933 PubMed 27114880
September 22, 2015
Intrinsically disordered caldesmon binds calmodulin via the “buttons on a string” mechanism
Sergei E. Permyakov, Eugene A. Permyakov, Vladimir N. Uversky
https://doi.org/10.7717/peerj.1265 PubMed 26417545
July 9, 2013
Looking at microbial metabolism by high-resolution 2H-NMR spectroscopy
Victor P. Kutyshenko, Petr M. Beskaravayny, Maxim V. Molchanov, Svetlana I. Paskevich, Dmitry A. Prokhorov, Vladimir N. Uversky
https://doi.org/10.7717/peerj.101 PubMed 23862103
February 12, 2013
Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome
Maria de Lourdes Coelho Ribeiro, Julio Espinosa, Sameen Islam, Osvaldo Martinez, Jayesh Jamnadas Thanki, Stephanie Mazariegos, Tam Nguyen, Maya Larina, Bin Xue, Vladimir N. Uversky
https://doi.org/10.7717/peerj.2 PubMed 23638354
October 27, 2015 - Version: 1
Structure and stability of recombinant bovine odorant-binding protein: III. Peculiarities of the wild type bOBP unfolding in crowded milieu
Olga V Stepanenko, Denis O Roginskii, Olesya V Stepanenko, Irina M Kuznetsova, Vladimir N Uversky, Konstantin K Turoverov
https://doi.org/10.7287/peerj.preprints.1454v1
October 27, 2015 - Version: 1
Structure and stability of recombinant bovine odorant-binding protein: II. Unfolding of the monomeric forms
Olga V Stepanenko, Denis O Roginskii, Olesya V Stepanenko, Irina M Kuznetsova, Vladimir N Uversky, Konstantin K Turoverov
https://doi.org/10.7287/peerj.preprints.1452v1
October 23, 2015 - Version: 1
Structure and stability of recombinant bovine odorant-binding protein: I. Design and analysis of monomeric mutants
Olga V Stepanenko, Denis O Roginskii, Olesya V Stepanenko, Irina M Kuznetsova, Vladimir N Uversky, Konstantin K Turoverov
https://doi.org/10.7287/peerj.preprints.1445v1
September 26, 2015 - Version: 1
Intrinsic disorder in biomarkers of insulin resistance, hypoadiponectinemia, and endothelial dysfunction among the type 2 diabetic patients
Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, Vladimir N. Uversky
https://doi.org/10.7287/peerj.preprints.1395v1
July 25, 2015 - Version: 1
Does intrinsically disordered caldesmon bind calmodulin via the “buttons on a string” mechanism?
Sergei E Permyakov, Eugene A Permyakov, Vladimir N Uversky
https://doi.org/10.7287/peerj.preprints.1261v1

Academic Editor on

February 3, 2023
Integrating multi-type aberrations from DNA and RNA through dynamic mapping gene space for subtype-specific breast cancer driver discovery
Jianing Xi, Zhen Deng, Yang Liu, Qian Wang, Wen Shi
https://doi.org/10.7717/peerj.14843
February 1, 2023
Development of a novel mathematical model that explains SARS-CoV-2 infection dynamics in Caco-2 cells
Vladimir Staroverov, Stepan Nersisyan, Alexei Galatenko, Dmitriy Alekseev, Sofya Lukashevich, Fedor Polyakov, Nikita Anisimov, Alexander Tonevitsky
https://doi.org/10.7717/peerj.14828
January 25, 2023
Effects of different proportions of stevia stalk on nutrient utilization and rumen fermentation in ruminal fluid derived from sheep
Xia Zhang, Ting Jiao, Shumin Ma, Xin Chen, Zhengwen Wang, Shengguo Zhao, Yue Ren
https://doi.org/10.7717/peerj.14689 PubMed 36718442
January 25, 2023
Comparison of urine proteomes from tumor-bearing mice with those from tumor-resected mice
Ziqi Heng, Chenyang Zhao, Youhe Gao
https://doi.org/10.7717/peerj.14737 PubMed 36718454
January 17, 2023
Solithromycin inhibits IL-13-induced goblet cell hyperplasia and MUC5AC, CLCA1, and ANO1 in human bronchial epithelial cells
Yasuhiro Kimura, Masahiro Shinoda, Masaharu Shinkai, Takeshi Kaneko
https://doi.org/10.7717/peerj.14695 PubMed 36684665
December 13, 2022
Hygiene of housing conditions and proinflammatory signals alter gene expressions in porcine adipose tissues and blood cells
Audrey Quéméner, Marie-Hélène Perruchot, Frédéric Dessauge, Annie Vincent, Elodie Merlot, Nathalie Le Floch, Isabelle Louveau
https://doi.org/10.7717/peerj.14405 PubMed 36530394
December 2, 2022
Transcriptome-wide identification of WRKY transcription factors and their expression profiles under different stress in Cynanchum thesioides
Xiaoyao Chang, Zhongren Yang, Xiaoyan Zhang, Fenglan Zhang, Xiumei Huang, Xu Han
https://doi.org/10.7717/peerj.14436 PubMed 36518281
November 25, 2022
Combined transcriptome and proteome analysis of yak PASMCs under hypoxic and normoxic conditions
Lan Zhang, Yiyang Zhang, Juan Zhou, Yifan Yao, Rui Li, Manlin Zhou, Shuwu Chen, Zilin Qiao, Kun Yang
https://doi.org/10.7717/peerj.14369 PubMed 36452079
November 21, 2022
A new species and new records species of Pluteus from Xinjiang Uygur Autonomous Region, China
Zheng-xiang Qi, Ke-qing Qian, Jia-jun Hu, Yang Wang, Dong-mei Wu, Neng Gao, Pei-Song Jia, Zhen-hao Zhang, Bo Zhang, Yu Li
https://doi.org/10.7717/peerj.14298 PubMed 36438581
November 7, 2022
AAA+ proteases: the first line of defense against mitochondrial damage
Gautam Pareek
https://doi.org/10.7717/peerj.14350 PubMed 36389399
October 17, 2022
isomiRTar: a comprehensive portal of pan-cancer 5′-isomiR targeting
Stepan Nersisyan, Aleksandra Gorbonos, Alexey Makhonin, Anton Zhiyanov, Maxim Shkurnikov, Alexander Tonevitsky
https://doi.org/10.7717/peerj.14205 PubMed 36275459
October 14, 2022
RFfiller: a robust and fast statistical algorithm for gap filling in draft genomes
Firaol Dida Midekso, Gangman Yi
https://doi.org/10.7717/peerj.14186 PubMed 36262414
October 3, 2022
Genome-wide identification, phylogenetic and expression pattern analysis of Dof transcription factors in blueberry (Vaccinium corymbosum L.)
Tianjie Li, Xiaoyu Wang, Dinakaran Elango, Weihua Zhang, Min Li, Fan Zhang, Qi Pan, Ying Wu
https://doi.org/10.7717/peerj.14087 PubMed 36213501
September 30, 2022
An in silico study of how histone tail conformation affects the binding affinity of ING family proteins
Nadir Gül, Ahmet Yıldız
https://doi.org/10.7717/peerj.14029 PubMed 36199288
September 30, 2022
Rapid restructurization of conformationally-distinct alpha-synuclein amyloid fibrils at an elevated temperature
Mantas Ziaunys, Andrius Sakalauskas, Kamile Mikalauskaite, Vytautas Smirnovas
https://doi.org/10.7717/peerj.14137 PubMed 36199282
September 14, 2022
Phenotypic spectrum of FGF10-related disorders: a systematic review
Katarzyna Bzdega, Justyna A. Karolak
https://doi.org/10.7717/peerj.14003 PubMed 36124135
August 25, 2022
Evolution of pathogenicity in obligate fungal pathogens and allied genera
Moytri RoyChowdhury, Jake Sternhagen, Ya Xin, Binghai Lou, Xiaobai Li, Chunnan Li
https://doi.org/10.7717/peerj.13794 PubMed 36042858
August 22, 2022
Recapitulating human ovarian aging using random walks
Joshua Johnson, John W. Emerson, Sean D. Lawley
https://doi.org/10.7717/peerj.13941 PubMed 36032944
August 2, 2022
Differential gene expression analysis after DAPK1 knockout in hepatocellular carcinoma cells
Yuanqi Li, Hui Huang, Huajun Yu, Ting Mo, Ting Wei, Guodan Li, Yufang Jia, Xiaoqin Huang, Mingjin Tu, Xiuwen Yan, Haitao Zhang
https://doi.org/10.7717/peerj.13711 PubMed 35935258
July 22, 2022
Analysis of microRNA expression profiles in exosomes derived from acute myeloid leukemia by p62 knockdown and effect on angiogenesis
Chuan Li, Xinyi Long, Peiqi Liang, Zhuogang Liu, Chen Wang, Rong Hu
https://doi.org/10.7717/peerj.13498 PubMed 35898936
July 14, 2022
Effects of commercial beverages on the neurobehavioral motility of Caenorhabditis elegans
Wenjing Zhang, Nan Zhang, Shan Zheng, Wei Zhang, Jingjing Liu, Liwei He, Anastasia Ngozi Ezemaduka, Guojun Li, Junyu Ning, Bo Xian, Shan Gao
https://doi.org/10.7717/peerj.13563 PubMed 35855427
July 12, 2022
Prevalence of HPV genotypes and assessment of their clinical relevance in laryngeal squamous cell carcinoma in a northeastern state of Brazil—a retrospective study
Charlles Brito, Rachel D. Cossetti, Diego Agra de Souza, Marcos Catanha, Pablo de Matos Monteiro, Flavia Castello Branco Vidal
https://doi.org/10.7717/peerj.13684 PubMed 35846883
July 11, 2022
Food taboos during pregnancy: meta-analysis on cross cultural differences suggests specific, diet-related pressures on childbirth among agriculturalists
Ornella Maggiulli, Fabrizio Rufo, Sarah E. Johns, Jonathan C.K. Wells
https://doi.org/10.7717/peerj.13633 PubMed 35846875
July 6, 2022
Ferroptotic cardiomyocyte-derived exosomes promote cardiac macrophage M1 polarization during myocardial infarction
Shengjia Sun, Yurong Wu, Alimujiang Maimaitijiang, Qingyu Huang, Qiying Chen
https://doi.org/10.7717/peerj.13717 PubMed 35818358
July 5, 2022
Surface cysteine to serine substitutions in IL-18 reduce aggregation and enhance activity
Jirakrit Saetang, Niran Roongsawang, Surasak Sangkhathat, Supayang Piyawan Voravuthikunchai, Natnaree Sangkaew, Napat Prompat, Teerapol Srichana, Varomyalin Tipmanee
https://doi.org/10.7717/peerj.13626 PubMed 35811828
July 4, 2022
Effect of icaritin on autophagy-related protein expression in TDP-43-transfected SH-SY5Y cells
Yanjun Zhou, Nanqu Huang, Yuanyuan Li, Zhisheng Ba, Yong Luo
https://doi.org/10.7717/peerj.13703 PubMed 35811810
June 9, 2022
Long noncoding RNA Gm31629 promotes bone regeneration by maintaining bone marrow mesenchymal stem cells activity
Guangping Cai, Ye Xiao, Mi Yang, Qi Guo, Tian Su, Yalin Liu, Tiejian Jiang, Chun Li
https://doi.org/10.7717/peerj.13475 PubMed 35702257
June 8, 2022
DeephageTP: a convolutional neural network framework for identifying phage-specific proteins from metagenomic sequencing data
Yunmeng Chu, Shun Guo, Dachao Cui, Xiongfei Fu, Yingfei Ma
https://doi.org/10.7717/peerj.13404 PubMed 35698617
June 7, 2022
Microfluidics-assisted electrospinning of aligned nanofibers for modeling intestine barriers
Wentao Su, Miao Zhang, Wenbo Wei, Haitao Wang, Wei Zhang, Zhongyu Li, Mingqian Tan, Zongzheng Chen
https://doi.org/10.7717/peerj.13513 PubMed 35694381
May 31, 2022
Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice
Dejun Zhu, Wenqing Zou, Xiangmei Cao, Weigang Xu, Zhaogang Lu, Yan Zhu, Xiaowen Hu, Jin Hu, Qing Zhu
https://doi.org/10.7717/peerj.13375 PubMed 35669949
May 31, 2022
Prospective quantitative gene expression analysis of kallikrein-related peptidase KLK10 as a diagnostic biomarker for childhood acute lymphoblastic leukemia
Shwan Majid Ahmad, Basima Sadq Ahmed, Karzan Ghafur Khidhir, Heshu Sulaiman Rahman
https://doi.org/10.7717/peerj.13489 PubMed 35669967
May 27, 2022
Anticancer mechanism of 7-α-hydroxyfrullanolide on microtubules and computational prediction of its target binding in triple-negative breast cancer cells
Siriphorn Chimplee, Carl Smythe, Varomyalin Tipmanee, Suchada Sukrong, Kanyanatt Kanokwiroon
https://doi.org/10.7717/peerj.13508 PubMed 35651747
May 25, 2022
Integrative analysis of transcriptome complexity in pig granulosa cells by long-read isoform sequencing
Shuxin Li, Jiarui Wang, Jiale Li, Meihong Yue, Chuncheng Liu, Libing Ma, Ying Liu
https://doi.org/10.7717/peerj.13446 PubMed 35637716
May 24, 2022
Chromatin accessibility landscape of stromal subpopulations reveals distinct metabolic and inflammatory features of porcine subcutaneous and visceral adipose tissue
Wenyang Sun, Tinghuan Zhang, Silu Hu, Qianzi Tang, Xi Long, Xu Yang, Shuangbao Gun, Lei Chen
https://doi.org/10.7717/peerj.13250 PubMed 35646489
May 17, 2022
TFR1 expression in induced sputum is associated with asthma severity
Yang Wang, li Feng Gu, Xincheng Zhao, Chengping Hu, Qiong Chen
https://doi.org/10.7717/peerj.13474 PubMed 35602900
May 11, 2022
Comparative proteomic analysis between mature and germinating seeds in Paris polyphylla var. yunnanensis
Li-Zhen Ling, Shu-Dong Zhang
https://doi.org/10.7717/peerj.13304 PubMed 35578673
May 9, 2022
Discovery of protein-based natural hydrogel from the girdle of the ‘sea cockroach’ Chiton articulatus (Chitonida: Chitonidae)
Emel Çakmak, Behlül Koc-Bilican, Omar Hernando Avila-Poveda, Tuğçe Karaduman, Demet Cansaran-Duman, Suzanne T. Williams, Murat Kaya
https://doi.org/10.7717/peerj.13386 PubMed 35573172
April 27, 2022
Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules
Stepan Nersisyan, Anton Zhiyanov, Maria Zakharova, Irina Ishina, Inna Kurbatskaia, Azad Mamedov, Alexei Galatenko, Maxim Shkurnikov, Alexander Gabibov, Alexander Tonevitsky
https://doi.org/10.7717/peerj.13354 PubMed 35502206
April 22, 2022
RFPDR: a random forest approach for plant disease resistance protein prediction
Diego Simón, Omar Borsani, Carla Valeria Filippi
https://doi.org/10.7717/peerj.11683 PubMed 35480565
April 19, 2022
Genome-wide identification, molecular characterization, and gene expression analyses of honeysuckle NHX antiporters suggest their involvement in salt stress adaptation
Luyao Huang, Zhuangzhuang Li, Chunyong Sun, Shijie Yin, Bin Wang, Tongyao Duan, Yang Liu, Jia Li, Gaobin Pu
https://doi.org/10.7717/peerj.13214 PubMed 35462769
April 19, 2022
Association of toll-like receptors single nucleotide polymorphisms with HBV and HCV infection: research status
Yaxin Xu, Wentao Xue, Hongwei Gao, Jiabo Cui, Lingzhi Zhao, Chongge You
https://doi.org/10.7717/peerj.13335 PubMed 35462764
April 12, 2022
Effect of extracts from eggs of Helix aspersa maxima and Helix aspersa aspersa snails on Caco-2 colon cancer cells
Magdalena Matusiewicz, Karolina Marczak, Barbara Kwiecińska, Julia Kupis, Klara Zglińska, Tomasz Niemiec, Iwona Kosieradzka
https://doi.org/10.7717/peerj.13217 PubMed 35433131
April 12, 2022
Expression and promoter analysis of MEP pathway enzyme-encoding genes in Pinus massoniana Lamb
Peihuang Zhu, Yu Chen, Fan Wu, Miaojing Meng, Kongshu Ji
https://doi.org/10.7717/peerj.13266 PubMed 35433125
March 30, 2022
Expression profiles and transcript properties of fast-twitch and slow-twitch muscles in a deep-sea highly migratory fish, Pseudocaranx dentex
Huan Wang, Busu Li, Long Yang, Chen Jiang, Tao Zhang, Shufang Liu, Zhimeng Zhuang
https://doi.org/10.7717/peerj.12720 PubMed 35378928
March 29, 2022
Comprehensive analysis of the correlations of S100B with hypoxia response and immune infiltration in hepatocellular carcinoma
Jia Yan, Ya jun Huang, Qing yu Huang, Peng Xia Liu, Chang Shan Wang
https://doi.org/10.7717/peerj.13201 PubMed 35368338
March 22, 2022
The prognostic and clinicopathological significance of desmoglein 2 in human cancers: a systematic review and meta-analysis
Jiantao Wang, Siyuan Hao, Junjie Gu, Sean G. Rudd, Yan Wang
https://doi.org/10.7717/peerj.13141 PubMed 35345582
March 22, 2022
Comparative transcriptome analysis of cold-tolerant and -sensitive asparagus bean under chilling stress and recovery
Mingjun Miao, Huaqiang Tan, Le Liang, Haitao Huang, Wei Chang, Jianwei Zhang, Ju Li, Yi Tang, Zhi Li, Yunsong Lai, Liang Yang, Huanxiu Li
https://doi.org/10.7717/peerj.13167 PubMed 35341039
March 21, 2022
Structural analysis of M1AP variants associated with severely impaired spermatogenesis causing male infertility
Umut Gerlevik, Mahmut Cerkez Ergoren, Osman Uğur Sezerman, Sehime Gulsun Temel
https://doi.org/10.7717/peerj.12947 PubMed 35341049
March 21, 2022
Relationship between circadian genes and memory impairment caused by sleep deprivation
Peng Ke, Chengjie Zheng, Feng Liu, LinJie Wu, Yijie Tang, Yanqin Wu, Dongdong Lv, Huangli Chen, Lin Qian, Xiaodan Wu, Kai Zeng
https://doi.org/10.7717/peerj.13165 PubMed 35341046
March 18, 2022
Complete chloroplast genome studies of different apple varieties indicated the origin of modern cultivated apples from Malus sieversii and Malus sylvestris
Xueli Li, Zhijie Ding, Haoyu Miao, Jinbo Bao, Xinmin Tian
https://doi.org/10.7717/peerj.13107 PubMed 35321410
March 16, 2022
A SNP variation in an expansin (EgExp4) gene affects height in oil palm
Suthasinee Somyong, Phakamas Phetchawang, Abdulloh Kafa Bihi, Chutima Sonthirod, Wasitthee Kongkachana, Duangjai Sangsrakru, Nukoon Jomchai, Wirulda Pootakham, Sithichoke Tangphatsornruang
https://doi.org/10.7717/peerj.13046 PubMed 35313525
March 9, 2022
Isolation and transcriptome analysis of a biotechnologically promising Black Sea protist, Thraustochytrium aureum ssp. strugatskii
Dmitrii K. Konstantinov, Aleksei Menzorov, Olga Krivenko, Alexey V. Doroshkov
https://doi.org/10.7717/peerj.12737 PubMed 35287351
March 9, 2022
Full-length transcriptome analysis of Adiantum flabellulatum gametophyte
Zeping Cai, Zhenyu Xie, Luyao Huang, Zixuan Wang, Min Pan, Xudong Yu, Shitao Xu, Jiajia Luo
https://doi.org/10.7717/peerj.13079 PubMed 35287343
March 4, 2022
Lung–brain ‘cross-talk’: systemic propagation of cytokines in the ARDS via the bloodstream using a blood transfusion model does not influence cerebral inflammatory response in pigs
René Rissel, Moritz Schaefer, Jens Kamuf, Robert Ruemmler, Julian Riedel, Katja Mohnke, Miriam Renz, Erik K. Hartmann, Alexander Ziebart
https://doi.org/10.7717/peerj.13024 PubMed 35265399
March 1, 2022
SEPALLATA­-like genes of Isatis indigotica can affect the architecture of the inflorescences and the development of the floral organs
Yan-Qin Ma, Zuo-Qian Pu, Xiao-Min Tan, Qi Meng, Kai-Li Zhang, Liu Yang, Ye-Ye Ma, Xuan Huang, Zi-Qin Xu
https://doi.org/10.7717/peerj.13034 PubMed 35251790
February 28, 2022
Analysis and comparison of protein secondary structures in the rachis of avian flight feathers
Pin-Yen Lin, Pei-Yu Huang, Yao-Chang Lee, Chen Siang Ng
https://doi.org/10.7717/peerj.12919 PubMed 35251779
February 23, 2022
Synovial fluid proteome profile of surgical versus chemical induced osteoarthritis in rabbits
Sharifah Zakiah Syed Sulaiman, Wei Miao Tan, Rozanaliza Radzi, Intan Nur Fatiha Shafie, Mokrish Ajat, Rozaihan Mansor, Suhaila Mohamed, Norasfaliza Rahmad, Angela Min Hwei Ng, Seng Fong Lau
https://doi.org/10.7717/peerj.12897 PubMed 35228907
February 22, 2022
Effects of starch sugar by-product on rumen in vitro digestibility, in situ disappearance rate, and milking productivity of the lactating dairy cow
Yongjun Choi, Suhun Kim, Sangrak Lee, Youngjun Na
https://doi.org/10.7717/peerj.12998 PubMed 35223213
February 14, 2022
Assessment of the effects of storage temperature on fatty acid analysis using dried blood spot cards from managed southern white rhinoceroses (Ceratotherium simum simum): implications for field collection and nutritional care
Jordan Wood, Larry J. Minter, Doug Bibus, Troy N. Tollefson, Kimberly Ange-van Heugten
https://doi.org/10.7717/peerj.12896 PubMed 35186484
February 8, 2022
Evaluating the therapeutic effect of tumor treating fields (TTFields) by monitoring the impedance across TTFields electrode arrays
Xing Li, Moshe Oziel, Boris Rubinsky
https://doi.org/10.7717/peerj.12877 PubMed 35186474
February 7, 2022
Effects of substituting soybean meal with corn on immune function and gene expression of gut TLR4 pathway of growing goats
Yan Cheng, Chao Yang, Wenxun Chen, Qiongxian Yan, Zhiliang Tan, Zhixiong He
https://doi.org/10.7717/peerj.12910 PubMed 35186490
February 7, 2022
Antioxidant and anti-inflammatory activities of durian (Durio zibethinus Murr.) pulp, seed and peel flour
Narin Charoenphun, Wiyada Kwanhian Klangbud
https://doi.org/10.7717/peerj.12933 PubMed 35186500
February 3, 2022
Identification and expression profiles of the YABBY transcription factors in wheat
Lidong Hao, Jinshan Zhang, Shubing Shi, Peng Li, Dandan Li, Tianjiao Zhang, Haibin Guo
https://doi.org/10.7717/peerj.12855 PubMed 35186463
February 2, 2022
Transcriptome analysis reveals the potential biological function of FSCN1 in HeLa cervical cancer cells
Fengqin Guo, Yanliang Liu, Yanxiang Cheng, Qifan Zhang, Weili Quan, Yaxun Wei, Li Hong
https://doi.org/10.7717/peerj.12909 PubMed 35178306
January 21, 2022
Genome-wide identification and expression analysis of the VQ gene family in Cucurbita pepo L.
Ke Xu, Ping Wang
https://doi.org/10.7717/peerj.12827 PubMed 35116202
January 20, 2022
Fast, low-memory detection and localization of large, polymorphic inversions from SNPs
Ronald J. Nowling, Fabian Fallas-Moya, Amir Sadovnik, Scott Emrich, Matthew Aleck, Daniel Leskiewicz, John G. Peters
https://doi.org/10.7717/peerj.12831 PubMed 35116204
January 11, 2022
CTRP3 as a novel biomarker in the plasma of Saudi children with autism
Manan Alhakbany, Laila Al-Ayadhi, Afaf El-Ansary
https://doi.org/10.7717/peerj.12630 PubMed 35047232
January 10, 2022
The speed of information propagation in the scientific network distorts biomedical research
Raul Rodriguez-Esteban
https://doi.org/10.7717/peerj.12764 PubMed 35070506
January 7, 2022
KIR gene content imputation from single-nucleotide polymorphisms in the Finnish population
Jarmo Ritari, Kati Hyvärinen, Jukka Partanen, Satu Koskela
https://doi.org/10.7717/peerj.12692 PubMed 35036093
January 5, 2022
Cancer types with high numbers of driver events are largely preventable
Aleksey V. Belikov, Sergey V. Leonov
https://doi.org/10.7717/peerj.12672 PubMed 35036090
December 22, 2021
The metabolism and role of free fatty acids in key physiological processes in insects of medical, veterinary and forensic importance
Agata Kaczmarek, Mieczysława Boguś
https://doi.org/10.7717/peerj.12563 PubMed 35036124
December 17, 2021
Inhibition of LINK-A lncRNA overcomes ibrutinib resistance in mantle cell lymphoma by regulating Akt/Bcl2 pathway
Ye Zhang, Peng Lu, Yan Zhou, Lifei Zhang
https://doi.org/10.7717/peerj.12571 PubMed 35003920
December 15, 2021
The cnidarian parasite Ceratonova shasta utilizes inherited and recruited venom-like compounds during infection
Benjamin Americus, Nicole Hams, Anna M. L. Klompen, Gema Alama-Bermejo, Tamar Lotan, Jerri L. Bartholomew, Stephen D. Atkinson
https://doi.org/10.7717/peerj.12606 PubMed 35003924
December 14, 2021
Comparison of African savanna elephant (Loxodonta africana) fatty acid profiles in whole blood, whole blood dried on blood spot cards, serum, and plasma
Jordan Wood, Larry J. Minter, Doug Bibus, Michael K. Stoskopf, Vivek Fellner, Kimberly Ange-van Heugten
https://doi.org/10.7717/peerj.12650 PubMed 35003934
December 9, 2021
Frequent, quantitative bone planar scintigraphy for determination of bone anabolism in growing mice
Ariane Zaloszyc, Claus Peter Schmitt, Amira Sayeh, Laetitia Higel, Catherine-Isabelle Gros, Fabien Bornert, Gaëlle Aubertin-Kirch, Jean-Philippe Dillenseger, Christian Goetz, André Constantinesco, Michel Fischbach, Seiamak Bahram, Philippe Choquet
https://doi.org/10.7717/peerj.12355 PubMed 34966570
November 24, 2021
Proteomic profiling of the endogenous peptides of MRSA and MSSA
Haixia Tu, Fei Xu, Yiwei Cheng, Qianglong Pan, Xiao Cai, Shouxing Wang, Shuting Ge, Min Cao, Dongming Su, Yan Li
https://doi.org/10.7717/peerj.12508 PubMed 34900427
November 19, 2021
Commercial utilities and future perspective of nanomedicines
Rishabha Malviya, Shivkanya Fuloria, Swati Verma, Vetriselvan Subramaniyan, Kathiresan V. Sathasivam, Vinoth Kumarasamy, Darnal Hari Kumar, Shalini Vellasamy, Dhanalekshmi Unnikrishnan Meenakshi, Shikha Yadav, Akanksha Sharma, Neeraj Kumar Fuloria
https://doi.org/10.7717/peerj.12392 PubMed 34820175
November 16, 2021
Gutter oil detection for food safety based on multi-feature machine learning and implementation on FPGA with approximate multipliers
Wei Jiang, Yuhanxiao Ma, Ruiqi Chen
https://doi.org/10.7717/peerj-cs.774
November 16, 2021
Interleukin 20 receptor A expression in colorectal cancer and its clinical significance
Rui Liu, Honghao Yin, Xin Sun, Songyi Liu, Ang Wang, Ying Wu, Yuan Yuan, Yuehua Gong, Chengzhong Xing
https://doi.org/10.7717/peerj.12467 PubMed 34820194
November 9, 2021
Gene polymorphisms in ULK1 and PIK3CA are associated with the risk of microscopic polyangiitis in the Guangxi Zhuang Autonomous Region in China
Yan Zhu, Jinlan Rao, Jingsi Wei, Liu Liu, Shanshan Huang, Jingjing Lan, Chao Xue, Wei Li
https://doi.org/10.7717/peerj.12377 PubMed 34820172
November 9, 2021
Enhanced soluble sugar content in tomato fruit using CRISPR/Cas9-mediated SlINVINH1 and SlVPE5 gene editing
Baike Wang, Ning Li, Shaoyong Huang, Jiahui Hu, Qiang Wang, Yaping Tang, Tao Yang, Patiguli Asmutola, Juan Wang, Qinghui Yu
https://doi.org/10.7717/peerj.12478 PubMed 34820200
November 5, 2021
Abundant CpG-sequences in human genomes inhibit KIR3DL2-expressing NK cells
Jason Pugh, Lisbeth Guethlein, Peter Parham
https://doi.org/10.7717/peerj.12258 PubMed 34760351
November 2, 2021
Differential p16 expression levels in the liver, hepatocytes and hepatocellular cell lines
Barbara Kramar, Dušan Šuput, Irina Milisav
https://doi.org/10.7717/peerj.12358 PubMed 34760375
November 1, 2021
PLGA-PEG-PLGA hydrogel with NEP1-40 promotes the functional recovery of brachial plexus root avulsion in adult rats
Wenlai Guo, Bingbing Pei, Zehui Li, Xiao Lan Ou, Tianwen Sun, Zhe Zhu
https://doi.org/10.7717/peerj.12269 PubMed 34760354
October 28, 2021
A novel role for apatinib in enhancing radiosensitivity in non-small cell lung cancer cells by suppressing the AKT and ERK pathways
Lin Li, Yuexian Li, Huawei Zou
https://doi.org/10.7717/peerj.12356 PubMed 34760374
October 28, 2021
fLPS 2.0: rapid annotation of compositionally-biased regions in biological sequences
Paul M. Harrison
https://doi.org/10.7717/peerj.12363 PubMed 34760378
October 26, 2021
Blood cells and hematological parameters of the mountain dragon, Diploderma micangshanensis (Squamata: Lacertilia: Agamidae)
Yinlong Bai, Guanglu Li, Shuaichao Lin, Jianli Xiong
https://doi.org/10.7717/peerj.12397 PubMed 34754628
October 21, 2021
Genome-wide identification and expression analysis of auxin response factors in peanut (Arachis hypogaea L.)
Peipei Li, Qian Ma, Chengxin Qu, Shuliang Zhu, Kunkun Zhao, Xingli Ma, Zhongfeng Li, Xingguo Zhang, Fangping Gong, Dongmei Yin
https://doi.org/10.7717/peerj.12319 PubMed 34721990
October 20, 2021
Development of a gene doping detection method to detect overexpressed human follistatin using an adenovirus vector in mice
Koki Yanazawa, Takehito Sugasawa, Kai Aoki, Takuro Nakano, Yasushi Kawakami, Kazuhiro Takekoshi
https://doi.org/10.7717/peerj.12285 PubMed 34721976
October 11, 2021
Extracellular pH, osmolarity, temperature and humidity could discourage SARS-CoV-2 cell docking and propagation via intercellular signaling pathways
Franco Cicconetti, Piero Sestili, Valeria Madiai, Maria Cristina Albertini, Luigi Campanella, Sofia Coppari, Daniele Fraternale, Bryan Saunders, Laura Teodori
https://doi.org/10.7717/peerj.12227 PubMed 34721966
October 4, 2021
Elemental analysis by Metallobalance provides a complementary support layer over existing blood biochemistry panel-based cancer risk assessment
Miho Kusakabe, Masahiro Sato, Yohko Nakamura, Haruo Mikami, Jason Lin, Hiroki Nagase
https://doi.org/10.7717/peerj.12247 PubMed 34707935
September 30, 2021
Highly comparable metabarcoding results from MGI-Tech and Illumina sequencing platforms
Sten Anslan, Vladimir Mikryukov, Kęstutis Armolaitis, Jelena Ankuda, Dagnija Lazdina, Kristaps Makovskis, Lars Vesterdal, Inger Kappel Schmidt, Leho Tedersoo
https://doi.org/10.7717/peerj.12254 PubMed 34703674
September 21, 2021
LitR directly upregulates autoinducer synthesis and luminescence in Aliivibrio logei
Sergey Bazhenov, Olga Melkina, Vadim Fomin, Ekaterina Scheglova, Pavel Krasnik, Svetlana Khrulnova, Gennadii Zavilgelsky, Ilya Manukhov
https://doi.org/10.7717/peerj.12030 PubMed 34616599
September 16, 2021
miR-1293 acts as a tumor promotor in lung adenocarcinoma via targeting phosphoglucomutase 5
Bing Chen, Shiya Zheng, Feng Jiang
https://doi.org/10.7717/peerj.12140 PubMed 34616611
September 14, 2021
Glucosylceramide synthase regulates hepatocyte repair after concanavalin A-induced immune-mediated liver injury
Jian Gan, Qin Gao, Li Li Wang, Ai Ping Tian, Long Dong Zhu, Li Ting Zhang, Wei Zhou, Xiao Rong Mao, Jun Feng Li
https://doi.org/10.7717/peerj.12138 PubMed 34611503
September 8, 2021
Apis mellifera propolis enhances apoptosis and invasion inhibition in head and neck cancer cells
Nattisa Niyomtham, Sittichai Koontongkaew, Boon-ek Yingyongnarongkul, Kusumawadee Utispan
https://doi.org/10.7717/peerj.12139 PubMed 34589307
September 1, 2021
Revisiting food-sourced vitamins for consumer diet and health needs: a perspective review, from vitamin classification, metabolic functions, absorption, utilization, to balancing nutritional requirements
Chigozie E. Ofoedu, Jude O. Iwouno, Ebelechukwu O. Ofoedu, Chika C. Ogueke, Victory S. Igwe, Ijeoma M. Agunwah, Arinze F. Ofoedum, James S. Chacha, Onyinye P. Muobike, Adedoyin O. Agunbiade, Njideka E. Njoku, Angela A. Nwakaudu, Nkiru E. Odimegwu, Onyekachi E. Ndukauba, Chukwuka U. Ogbonna, Joncer Naibaho, Maciej Korus, Charles Odilichukwu R. Okpala
https://doi.org/10.7717/peerj.11940 PubMed 34557342
August 26, 2021
Camostat mesilate inhibits pro-inflammatory cytokine secretion and improves cell viability by regulating MFGE8 and HMGN1 in lipopolysaccharide-stimulated DF-1 chicken embryo fibroblasts
Lin Yuan, Mengjie Li, Zhishuai Zhang, Wanli Li, Wei Jin, Mingfa Wang
https://doi.org/10.7717/peerj.12053 PubMed 34527443
August 25, 2021
Prevalence and characterization of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated from raw vegetables retailed in Southern Thailand
Chonticha Romyasamit, Phoomjai Sornsenee, Siriphorn Chimplee, Sitanun Yuwalaksanakun, Dechawat Wongprot, Phanvasri Saengsuwan
https://doi.org/10.7717/peerj.11787 PubMed 34527432
August 24, 2021
Protein function prediction with gene ontology: from traditional to deep learning models
Thi Thuy Duong Vu, Jaehee Jung
https://doi.org/10.7717/peerj.12019 PubMed 34513334
August 19, 2021
Inhibition of Kelch-like epichlorohydrin-related protein 1 promotes the progression and drug resistance of lung adenocarcinoma
Hong Gao, Peipei Tang, Kejie Ni, Lun Zhu, Song Chen, Yulong Zheng, Yufeng Wan
https://doi.org/10.7717/peerj.11908 PubMed 34466284
August 17, 2021
Integrated bioinformatics analysis of the NEDD4 family reveals a prognostic value of NEDD4L in clear-cell renal cell cancer
Hui Zhao, Junjun Zhang, Xiaoliang Fu, Dongdong Mao, Xuesen Qi, Shuai Liang, Gang Meng, Zewen Song, Ru Yang, Zhenni Guo, Binghua Tong, Meiqing Sun, Baile Zuo, Guoyin Li
https://doi.org/10.7717/peerj.11880 PubMed 34458018
August 13, 2021
Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction
Chao Luo, Xiongcai Zhou, Li Wang, Qinyu Zeng, Junhong Fan, Shuhua He, Haibo Zhang, Anyang Wei
https://doi.org/10.7717/peerj.11986 PubMed 34447638
August 11, 2021
Exploring the role of monocyte chemoattractant protein-1 in fibroblast-like synovial cells in rheumatoid arthritis
Xiang Tong, Dongdong Yu, Li Yu, Weiqian Chen, Yanling Wen, Pengcheng Gu
https://doi.org/10.7717/peerj.11973 PubMed 34447637
August 10, 2021
N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats
Yitong Pan, Shuna Yu, Jianxin Wang, Wanzhen Li, Huiting Li, Chen Bai, Yaxin Sheng, Ming Li, Chenchen Wang, Jiao Liu, Peitong Xie, Can Wang, Jiying Jiang, Jianguo Li
https://doi.org/10.7717/peerj.11909 PubMed 34434653
August 3, 2021
DUSP12 regulates the tumorigenesis and prognosis of hepatocellular carcinoma
Gaoda Ju, Tianhao Zhou, Rui Zhang, Xiaozao Pan, Bing Xue, Sen Miao
https://doi.org/10.7717/peerj.11929 PubMed 34414037
July 27, 2021
Proteomic analysis reveals some common proteins in the kidney stone matrix
Yuanyuan Yang, Senyuan Hong, Cong Li, Jiaqiao Zhang, Henglong Hu, Xiaolong Chen, Kehua Jiang, Fa Sun, Qing Wang, Shaogang Wang
https://doi.org/10.7717/peerj.11872 PubMed 34395096
July 26, 2021
Genomics pipelines to investigate susceptibility in whole genome and exome sequenced data for variant discovery, annotation, prediction and genotyping
Zeeshan Ahmed, Eduard Gibert Renart, Saman Zeeshan
https://doi.org/10.7717/peerj.11724 PubMed 34395068
July 22, 2021
Genome-wide identification and analysis of the YABBY gene family in Moso Bamboo (Phyllostachys edulis (Carrière) J. Houz)
Ruifang Ma, Bin Huang, Zhinuo Huang, Zhijun Zhang
https://doi.org/10.7717/peerj.11780 PubMed 34327057
July 14, 2021
Role of ferroptosis-related genes in prognostic prediction and tumor immune microenvironment in colorectal carcinoma
Chao Yang, Shuoyang Huang, Fengyu Cao, Yongbin Zheng
https://doi.org/10.7717/peerj.11745 PubMed 34316400
July 12, 2021
Long-term dynamics of Norovirus transmission in Japan, 2005–2019
Megumi Misumi, Hiroshi Nishiura
https://doi.org/10.7717/peerj.11769 PubMed 34306831
June 28, 2021
Helicobacter pylori prevalence in healthy Mexican children: comparison between two non-invasive methods
Verónica I. Martínez-Santos, Manuel Hernández Catalán, Luis Octavio Ojeda Salazar, Octavio Andrei Orozco Gómez, Sandra Ines Lorenzo, Rayver Santos Gómez, Norma S. Romero-Castro, Roxana Reyes Ríos, Dinorah Nashely Martinez Carrillo, Gloria Fernández-Tilapa
https://doi.org/10.7717/peerj.11546 PubMed 34249489
June 22, 2021
Methylation of CYP1A1 and VKORC1 promoter associated with stable dosage of warfarin in Chinese patients
Shiwei He, Yuan Wu, Shuidi Yan, Jumei Liu, Li Zhao, Huabin Xie, Shengxiang Ge, Huiming Ye
https://doi.org/10.7717/peerj.11549 PubMed 34221714
June 21, 2021
Retinal dysfunction induced in a mouse model of unilateral common carotid artery occlusion
Deokho Lee, Heonuk Jeong, Yukihiro Miwa, Ari Shinojima, Yusaku Katada, Kazuo Tsubota, Toshihide Kurihara
https://doi.org/10.7717/peerj.11665 PubMed 34221738
June 15, 2021
Genome-wide identification and characterization of UBP gene family in wheat (Triticum aestivum L.)
Miaoze Xu, Peng Jin, Tingting Liu, Shiqi Gao, Tianye Zhang, Fan Zhang, Xiaolei Han, Long He, Jianping Chen, Jian Yang
https://doi.org/10.7717/peerj.11594 PubMed 34178465
June 2, 2021
Expression and gene regulation network of TYMS and BCL2L1 in colorectal cancer based on data mining
Yanghua Jie, Xiaobei Yang, Weidong Chen
https://doi.org/10.7717/peerj.11368 PubMed 34141464
June 2, 2021
Dynamic residue interaction network analysis of the oseltamivir binding site of N1 neuraminidase and its H274Y mutation site conferring drug resistance in influenza A virus
Mohini Yadav, Manabu Igarashi, Norifumi Yamamoto
https://doi.org/10.7717/peerj.11552 PubMed 34141489
June 1, 2021
Promoting effect of rapamycin on osteogenic differentiation of maxillary sinus membrane stem cells
Yanjun Lin, Min Zhang, Lin Zhou, Xuxi Chen, Jiang Chen, Dong Wu
https://doi.org/10.7717/peerj.11513 PubMed 34141480
June 1, 2021
T-complex protein 1 subunit zeta-2 (CCT6B) deficiency induces murine teratospermia
Peiyin Yang, Wenjing Tang, Huiling Li, Rong Hua, Yan Yuan, Yue Zhang, Yunfei Zhu, Yiqiang Cui, Jiahao Sha
https://doi.org/10.7717/peerj.11545 PubMed 34141486
June 1, 2021
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study
Pengfei Li, Jie Sun, Yuanyuan Ruan, Lujun Song
https://doi.org/10.7717/peerj.11551 PubMed 34141488
May 26, 2021
The GRAS gene family in watermelons: identification, characterization and expression analysis of different tissues and root-knot nematode infestations
Gongbo Lv, Xing Zheng, Yitian Duan, Yunyong Wen, Bin Zeng, Mingqiang Ai, Bin He
https://doi.org/10.7717/peerj.11526 PubMed 34123598
May 25, 2021
Evaluation of pro-apoptotic potential of taxifolin against liver cancer
Sania Safdar Butt, Khushbukhat Khan, Yasmin Badshah, Mehak Rafiq, Maria Shabbir
https://doi.org/10.7717/peerj.11276 PubMed 34113483
May 17, 2021
Trp-574-Leu mutation in wild mustard (Sinapis arvensis L.) as a result of als inhibiting herbicide applications
Bahadir Sin, İzzet Kadıoglu
https://doi.org/10.7717/peerj.11385 PubMed 34046259
May 14, 2021
Oxidative stress induces cell death partially by decreasing both mRNA and protein levels of nicotinamide phosphoribosyltransferase in differentiated PC12 cells
Cuiyan Zhou, Weihai Ying
https://doi.org/10.7717/peerj.11401 PubMed 34040894
May 14, 2021
The relationship between PLOD1 expression level and glioma prognosis investigated using public databases
Lei Tian, Huandi Zhou, Guohui Wang, Wen yan Wang, Yuehong Li, Xiaoying Xue
https://doi.org/10.7717/peerj.11422 PubMed 34040895
May 13, 2021
Identification of the biological function of miR-9 in spinal cord ischemia-reperfusion injury in rats
Fengshou Chen, Jie Han, Xiaoqian Li, Zaili Zhang, Dan Wang
https://doi.org/10.7717/peerj.11440 PubMed 34035993
May 12, 2021
Genome-wide identification of the Tubby-Like Protein (TLPs) family in medicinal model plant Salvia miltiorrhiza
Kai Wang, Yating Cheng, Li Yi, Hailang He, Shaofeng Zhan, Peng Yang
https://doi.org/10.7717/peerj.11403 PubMed 34026360
May 11, 2021
Prokaryotic communities from a lava tube cave in La Palma Island (Spain) are involved in the biogeochemical cycle of major elements
Jose Luis Gonzalez-Pimentel, Tamara Martin-Pozas, Valme Jurado, Ana Zelia Miller, Ana Teresa Caldeira, Octavio Fernandez-Lorenzo, Sergio Sanchez-Moral, Cesareo Saiz-Jimenez
https://doi.org/10.7717/peerj.11386 PubMed 34026356
May 6, 2021
Genome-wide identification, classification and expression profile analysis of the HSF gene family in Hypericum perforatum
Li Zhou, Xiaoding Yu, Donghao Wang, Lin Li, Wen Zhou, Qian Zhang, Xinrui Wang, Sumin Ye, Zhezhi Wang
https://doi.org/10.7717/peerj.11345 PubMed 33996286
May 5, 2021
Construction of an immune-related signature with prognostic value for colon cancer
Yunxia Lv, Xinyi Wang, Yu Ren, Xiaorui Fu, Taiyuan Li, Qunguang Jiang
https://doi.org/10.7717/peerj.10812 PubMed 33996273
May 3, 2021
Prediction of DNA binding proteins using local features and long-term dependencies with primary sequences based on deep learning
Guobin Li, Xiuquan Du, Xinlu Li, Le Zou, Guanhong Zhang, Zhize Wu
https://doi.org/10.7717/peerj.11262 PubMed 33986992
May 3, 2021
Centromere protein N may be a novel malignant prognostic biomarker for hepatocellular carcinoma
Qingqing Wang, Xiaoyan Yu, Zhewen Zheng, Fengxia Chen, Ningning Yang, Yunfeng Zhou
https://doi.org/10.7717/peerj.11342 PubMed 33987018
April 30, 2021
Mycophenolate suppresses inflammation by inhibiting prostaglandin synthases: a study of molecular and experimental drug repurposing
Fahad Al-Hizab, Mahmoud Kandeel
https://doi.org/10.7717/peerj.11360 PubMed 33987026
April 22, 2021
Transcriptome analysis of the liver of Eospalax fontanierii under hypoxia
Zhiqiang Hao, Lulu Xu, Li Zhao, Jianping He, Guanglin Li, Jingang Li
https://doi.org/10.7717/peerj.11166 PubMed 33981491
April 21, 2021
Identification of a novel autophagy signature for predicting survival in patients with lung adenocarcinoma
Jin Duan, Youming Lei, Guoli Lv, Yinqiang Liu, Wei Zhao, Qingmei Yang, Xiaona Su, Zhijian Song, Leilei Lu, Yunfei Shi
https://doi.org/10.7717/peerj.11074 PubMed 33976960
April 20, 2021
Widely assumed phenotypic associations in Cannabis sativa lack a shared genetic basis
Daniela Vergara, Cellene Feathers, Ezra L. Huscher, Ben Holmes, Jacob A. Haas, Nolan C. Kane
https://doi.org/10.7717/peerj.10672 PubMed 33976953
April 20, 2021
Anti-atherosclerotic vaccination against Porphyromonas gingivalis as a potential comparator of statin in mice
Hyun-Su Ha, Tae Young Kim, Soo Jung Han, Hak-Joon Sung, Kyoung Yul Seo, Jong-Won Ha
https://doi.org/10.7717/peerj.11293 PubMed 33976982
April 13, 2021
Identification of a ferroptosis-related gene signature (FRGS) for predicting clinical outcome in lung adenocarcinoma
Sheng Wang, Chunlei Wu, Dehua Ma, Quanteng Hu
https://doi.org/10.7717/peerj.11233 PubMed 33954048
April 7, 2021
Analysis of differences in the transcriptomic profiles of eutopic and ectopic endometriums in women with ovarian endometriosis
Xiao Feng, Lingbin Qi, Xiaoyu Xu, Yun Feng, Xiaoming Gong, Aixingzi Aili, Yu Chen, Zhigang Xue, Jinfeng Xue, Xiaowen Tong
https://doi.org/10.7717/peerj.11045 PubMed 33868805
April 2, 2021
Exosomes derived from plasma: promising immunomodulatory agents for promoting angiogenesis to treat radiation-induced vascular dysfunction
Yanxi Li, Ping Lyu, Yiting Ze, Peiran Li, Xinyi Zeng, Yixin Shi, Bingrun Qiu, Ping Gong, Yang Yao
https://doi.org/10.7717/peerj.11147 PubMed 33859878
March 31, 2021
Ameliorative effect of apelin-13 against renal complications in L-NAME-induced preeclampsia in rats
Reham Z. Hamza, Abdel Aziz A. Diab, Mansour H. Zahra, Ali K. Asalah, Mai S. Attia, Suzan MM Moursi
https://doi.org/10.7717/peerj.11110 PubMed 33850656
March 17, 2021
Bioinformatics analysis identified CDC20 as a potential drug target for cholangiocarcinoma
Prin Sungwan, Worachart Lert-itthiporn, Atit Silsirivanit, Nathakan Klinhom-on, Seiji Okada, Sopit Wongkham, Wunchana Seubwai
https://doi.org/10.7717/peerj.11067 PubMed 33777535
March 3, 2021
Evaluation of female Aedes aegypti proteome via LC-ESI-MS/MS using two protein extraction methods
Abubakar Shettima, Intan H. Ishak, Syahirah Hanisah Abdul Rais, Hadura Abu Hasan, Nurulhasanah Othman
https://doi.org/10.7717/peerj.10863 PubMed 33717682
March 3, 2021
Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K+ channels inhibition
Hyun Jong Kim, Seorin Park, Hui Young Shin, Yu Ran Nam, Phan Thi Lam Hong, Young-Won Chin, Joo Hyun Nam, Woo Kyung Kim
https://doi.org/10.7717/peerj.10973 PubMed 33717700
March 2, 2021
Undercarboxylated osteocalcin inhibits the early differentiation of osteoclast mediated by Gprc6a
Hailong Wang, Jinqiao Li, Zihan Xu, Feng Wu, Hongyu Zhang, Chao Yang, Jian Chen, Bai Ding, Xiukun Sui, Zhifeng Guo, Yinghui Li, Zhongquan Dai
https://doi.org/10.7717/peerj.10898 PubMed 33717684
March 1, 2021
Phenotype study of multifoliolate leaf formation in Trifolium alexandrinum L.
Devendra Ram Malaviya, Ajoy Kumar Roy, Pankaj Kaushal, Shalini Pathak, Ruslan Kalendar
https://doi.org/10.7717/peerj.10874 PubMed 33717683
February 25, 2021
The Doublesex/Mab-3 domain transcription factor DMD-10 regulates ASH-dependent behavioral responses
Julia Durbeck, Celine Breton, Michael Suter, Eric S. Luth, Annette M. McGehee
https://doi.org/10.7717/peerj.10892 PubMed 33665029
February 3, 2021
The expression characteristics and prognostic roles of autophagy-related genes in gastric cancer
Mengya Wang, Jingjing Jing, Hao Li, Jingwei Liu, Yuan Yuan, Liping Sun
https://doi.org/10.7717/peerj.10814 PubMed 33604190
February 2, 2021
Identification of candidate genes influencing anthocyanin biosynthesis during the development and ripening of red and white strawberry fruits via comparative transcriptome analysis
Fengli Zhao, Pan Song, Xiangfen Zhang, Gang Li, Panpan Hu, Ali Aslam, Xia Zhao, Houcheng Zhou
https://doi.org/10.7717/peerj.10739 PubMed 33604178
February 2, 2021
Epigenetic identification of mitogen-activated protein kinase 10 as a functional tumor suppressor and clinical significance for hepatocellular carcinoma
Liping Tang, Shasha Zhu, Weiyan Peng, Xuedong Yin, Cui Tan, Yaying Yang
https://doi.org/10.7717/peerj.10810 PubMed 33604188
February 1, 2021
TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese population
Jiaying Li, Hongjiao Wu, Hui Gao, Ruihuan Kou, Yuning Xie, Zhi Zhang, Xuemei Zhang
https://doi.org/10.7717/peerj.10754 PubMed 33585082
January 19, 2021
The functional analysis of ABCG transporters in the adaptation of pigeon pea (Cajanus cajan) to abiotic stresses
Lili Niu, Hanghang Li, Zhihua Song, Biying Dong, Hongyan Cao, Tengyue Liu, Tingting Du, Wanlong Yang, Rohul Amin, Litao Wang, Qing Yang, Dong Meng, Yujie Fu
https://doi.org/10.7717/peerj.10688 PubMed 33552725
January 15, 2021
High expression of MAPK-14 promoting the death of chondrocytes is an important signal of osteoarthritis process
Zhiqin Deng, Xiaotian Hu, Murad Alahdal, Jianquan Liu, Zhe Zhao, Xiaoqiang Chen, Junxiong Xie, Li Duan, Daping Wang, Wencui Li
https://doi.org/10.7717/peerj.10656 PubMed 33520453
January 6, 2021
Biochemical characterization and inhibition of thermolabile hemolysin from Vibrio parahaemolyticus by phenolic compounds
Luis E. Vazquez-Morado, Ramon E. Robles-Zepeda, Adrian Ochoa-Leyva, Aldo A. Arvizu-Flores, Adriana Garibay-Escobar, Francisco Castillo-Yañez, Alonso A. Lopez-zavala
https://doi.org/10.7717/peerj.10506 PubMed 33505784
December 18, 2020
The p53 signaling pathway of the large yellow croaker (Larimichthys crocea) responds to acute cold stress: evidence via spatiotemporal expression analysis of p53, p21, MDM2, IGF-1, Gadd45, Fas, and Akt
Baoying Qian, Xin Qi, Yi Bai, Yubo Wu
https://doi.org/10.7717/peerj.10532 PubMed 33384900
December 16, 2020
Transcriptome profiling reveals Silibinin dose-dependent response network in non-small lung cancer cells
Jagan Mohan Kaipa, Vytaute Starkuviene, Holger Erfle, Roland Eils, Evgeny Gladilin
https://doi.org/10.7717/peerj.10373 PubMed 33362957
December 16, 2020
Characterization of DNA methylation in Malawian Mycobacterium tuberculosis clinical isolates
Victor Ndhlovu, Anmol Kiran, Derek J. Sloan, Wilson Mandala, Marriott Nliwasa, Dean B. Everett, Benjamin Kumwenda, Mphatso Mwapasa, Konstantina Kontogianni, Mercy Kamdolozi, Elizabeth Corbett, Maxine Caws, Gerry Davies
https://doi.org/10.7717/peerj.10432 PubMed 33362962
December 11, 2020
Driver versus navigator causation in biology: the case of insulin and fasting glucose
Manawa Diwekar-Joshi, Milind Watve
https://doi.org/10.7717/peerj.10396 PubMed 33365205
December 7, 2020
Identification of key genes and pathways in endometriosis by integrated expression profiles analysis
Ding Cui, Yang Liu, Junyan Ma, Kaiqing Lin, Kaihong Xu, Jun Lin
https://doi.org/10.7717/peerj.10171 PubMed 33354413
December 3, 2020
Comprehensive analysis of circRNA expression profiles and circRNA-associated competing endogenous RNA networks in IgA nephropathy
Haiyang Liu, Di Liu, Yexin Liu, Ming Xia, Yan Li, Mei Li, Hong Liu
https://doi.org/10.7717/peerj.10395 PubMed 33344076
December 2, 2020
Phospho-islands and the evolution of phosphorylated amino acids in mammals
Mikhail Moldovan, Mikhail S. Gelfand
https://doi.org/10.7717/peerj.10436 PubMed 33344082
December 1, 2020
Comprehensive pathway-related genes signature for prognosis and recurrence of ovarian cancer
Xinnan Zhao, Miao He
https://doi.org/10.7717/peerj.10437 PubMed 33344083
November 24, 2020
Classification of ovarian cancer associated with BRCA1 mutations, immune checkpoints, and tumor microenvironment based on immunogenomic profiling
Yousheng Wei, Tingyu Ou, Yan Lu, Guangteng Wu, Ying Long, Xinbin Pan, Desheng Yao
https://doi.org/10.7717/peerj.10414 PubMed 33282564
November 23, 2020
Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics analysis
Jingyi Ding, Yanxi Liu, Yu Lai
https://doi.org/10.7717/peerj.10419 PubMed 33282565
November 20, 2020
Loss of HOXB3 correlates with the development of hormone receptor negative breast cancer
Lizhe Zhu, Shibo Yu, Siyuan Jiang, Guanqun Ge, Yu Yan, Yuhui Zhou, Ligang Niu, Jianjun He, Yu Ren, Bin Wang
https://doi.org/10.7717/peerj.10421 PubMed 33240685
November 5, 2020
An updated evolutionary study of the Notch family reveals a new ancient origin and novel invariable motifs as potential pharmacological targets
Dimitrios Vlachakis, Louis Papageorgiou, Ariadne Papadaki, Maria Georga, Sofia Kossida, Elias Eliopoulos
https://doi.org/10.7717/peerj.10334 PubMed 33194454
November 4, 2020
Prognostic model of invasive ductal carcinoma of the breast based on differentially expressed glycolysis-related genes
Xiaoping Li, Qihe Yu, Jishang Chen, Hui Huang, Zhuangsheng Liu, Chengxing Wang, Yaoming He, Xin Zhang, Weiwen Li, Chao Li, Jinglin Zhao, Wansheng Long
https://doi.org/10.7717/peerj.10249 PubMed 33194424
October 30, 2020
Genetic variations and dog breed identification using inter-simple sequence repeat markers coupled with high resolution melting analysis
Wannapimol Kriangwanich, Korakot Nganvongpanit, Kittisak Buddhachat, Puntita Siengdee, Siriwadee Chomdej, Siriluck Ponsuksili, Chatchote Thitaram
https://doi.org/10.7717/peerj.10215 PubMed 33194413
October 28, 2020
Identification and expression analysis of the WRKY gene family during different developmental stages in Lycium ruthenicum Murr. fruit
Richard John Tiika, Jia Wei, Rui Ma, Hongshan Yang, Guangxin Cui, Huirong Duan, Yanjun Ma
https://doi.org/10.7717/peerj.10207 PubMed 33194409
October 21, 2020
Immunoglobulin superfamily member 10 is a novel prognostic biomarker for breast cancer
Mengxue Wang, Meng Dai, Yu-shen Wu, Ziying Yi, Yunhai Li, Guosheng Ren
https://doi.org/10.7717/peerj.10128 PubMed 33150070
October 20, 2020
Mining the potential prognostic value of synaptosomal-associated protein 25 (SNAP25) in colon cancer based on stromal-immune score
Jinyan Zou, Darong Duan, Changfa Yu, Jie Pan, Jinwei Xia, Zaixing Yang, Shasha Cai
https://doi.org/10.7717/peerj.10142 PubMed 33150073
October 20, 2020
miR-29a-3p directly targets Smad nuclear interacting protein 1 and inhibits the migration and proliferation of cervical cancer HeLa cells
Ying Chen, Weiji Zhang, Lijun Yan, Peng Zheng, Jin Li
https://doi.org/10.7717/peerj.10148 PubMed 33150075
October 20, 2020
Structure and expression analysis of seven salt-related ERF genes of Populus
Juanjuan Huang, Shengji Wang, Xingdou Wang, Yan Fan, Youzhi Han
https://doi.org/10.7717/peerj.10206 PubMed 33150090
October 5, 2020
Immune cell landscape analysis reveals prognostic immune cells and its potential mechanism in squamous cell lung carcinoma
Yongyong Wang, Jianji Guo
https://doi.org/10.7717/peerj.9996 PubMed 33083119
September 29, 2020
A glycolysis-related gene pairs signature predicts prognosis in patients with hepatocellular carcinoma
Weige Zhou, Shijing Zhang, Zheyou Cai, Fei Gao, Wenhui Deng, Yi Wen, Zhen-wen Qiu, Zheng-kun Hou, Xin-Lin Chen
https://doi.org/10.7717/peerj.9944 PubMed 33062428
September 22, 2020
Flavoured water consumption alters pharmacokinetic parameters and increases exposure of erlotinib and gefitinib in a preclinical study using Wistar rats
Aliyah Almomen, Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata, Amal Alsubaie
https://doi.org/10.7717/peerj.9881 PubMed 33024629
September 21, 2020
Θ-SEIHRD mathematical model of Covid19-stability analysis using fast-slow decomposition
OPhir Nave, Israel Hartuv, Uziel Shemesh
https://doi.org/10.7717/peerj.10019 PubMed 33005495
September 16, 2020
Galectin-3 not Galectin-9 as a candidate prognosis marker for hepatocellular carcinoma
Fei Kong, Meishan Jin, Donghui Cao, Zhifang Jia, Yawen Liu, Jing Jiang
https://doi.org/10.7717/peerj.9949 PubMed 32995093
September 15, 2020
Estimating the impact of mobility patterns on COVID-19 infection rates in 11 European countries
Patrick Bryant, Arne Elofsson
https://doi.org/10.7717/peerj.9879 PubMed 32983643
September 14, 2020
Potential role of cellular miRNAs in coronavirus-host interplay
Stepan Nersisyan, Narek Engibaryan, Aleksandra Gorbonos, Ksenia Kirdey, Alexey Makhonin, Alexander Tonevitsky
https://doi.org/10.7717/peerj.9994 PubMed 32983652
September 8, 2020
Cannonball jellyfish digestion: an insight into the lipolytic enzymes of the digestive system
Raul B. Martínez-Pérez, Jorge A. Rodríguez, Luis Alonso Leyva Soto, Pablo Gortáres-Moroyoqui, Lourdes M. Diaz-Tenorio
https://doi.org/10.7717/peerj.9794 PubMed 33194347
September 7, 2020
Overexpression of KIAA1199 is an independent prognostic marker in laryngeal squamous cell carcinoma
Meixiang Huang, Feifei Liao, Yexun Song, Gang Zuo, Guolin Tan, Ling Chu, Tiansheng Wang
https://doi.org/10.7717/peerj.9637 PubMed 33194340
August 27, 2020
Plastid transit peptides—where do they come from and where do they all belong? Multi-genome and pan-genomic assessment of chloroplast transit peptide evolution
Ryan W. Christian, Seanna L. Hewitt, Grant Nelson, Eric H. Roalson, Amit Dhingra
https://doi.org/10.7717/peerj.9772 PubMed 32913678
August 24, 2020
Mining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment
Jiong Ma, Pu Cheng, Xuejun Chen, Chunxia Zhou, Wei Zheng
https://doi.org/10.7717/peerj.9627 PubMed 32904067
August 21, 2020
Human granulocyte-colony stimulating factor (G-CSF)/stem cell factor (SCF) fusion proteins: design, characterization and activity
Gitana Mickiene, Indrė Dalgėdienė, Gintautas Zvirblis, Zilvinas Dapkunas, Ieva Plikusiene, Ernesta Buzavaite-Verteliene, Zigmas Balevičius, Audronė Rukšėnaitė, Milda Pleckaityte
https://doi.org/10.7717/peerj.9788 PubMed 32884863
August 19, 2020
Transcriptomic analysis highlights cochlear inflammation associated with age-related hearing loss in C57BL/6 mice using next generation sequencing
Zhongwu Su, Hao Xiong, Yi Liu, Jiaqi Pang, Hanqing Lin, Weijian Zhang, Yiqing Zheng
https://doi.org/10.7717/peerj.9737 PubMed 32879802
August 14, 2020
Methylene blue inhibits nucleation and elongation of SOD1 amyloid fibrils
Greta Musteikyte, Mantas Ziaunys, Vytautas Smirnovas
https://doi.org/10.7717/peerj.9719 PubMed 32864220
August 6, 2020
Dissecting molecular network structures using a network subgraph approach
Chien-Hung Huang, Efendi Zaenudin, Jeffrey J.P. Tsai, Nilubon Kurubanjerdjit, Eskezeia Y. Dessie, Ka-Lok Ng
https://doi.org/10.7717/peerj.9556 PubMed 33005483
August 3, 2020
Identification of DNA methylation patterns and biomarkers for clear-cell renal cell carcinoma by multi-omics data analysis
Pengfei Liu, Weidong Tian
https://doi.org/10.7717/peerj.9654 PubMed 32832275
July 28, 2020
Five genes influenced by obesity may contribute to the development of thyroid cancer through the regulation of insulin levels
Jiaming Chen, Hongbao Cao, Meng Lian, Jugao Fang
https://doi.org/10.7717/peerj.9302 PubMed 33240576
July 28, 2020
Proteomic analysis of human cervical adenocarcinoma mucus to identify potential protein biomarkers
Zhifang Ma, Jie Chen, Ting Luan, Chengzhuo Chu, Wangfei Wu, Yichao Zhu, Yun Gu
https://doi.org/10.7717/peerj.9527 PubMed 33194326
July 28, 2020
Identification of 10 Hub genes related to the progression of colorectal cancer by co-expression analysis
Jie Meng, Rui Su, Yun Liao, Yanyan Li, Ling Li
https://doi.org/10.7717/peerj.9633 PubMed 33240582
July 22, 2020
Role of methyltransferase-like enzyme 3 and methyltransferase-like enzyme 14 in urological cancers
Zijia Tao, Yiqiao Zhao, Xiaonan Chen
https://doi.org/10.7717/peerj.9589 PubMed 32765970
July 9, 2020
Identifying hub genes of papillary thyroid carcinoma in the TCGA and GEO database using bioinformatics analysis
Ying Wan, Xiaolian Zhang, Huilin Leng, Weihua Yin, Wenxing Zeng, Congling Zhang
https://doi.org/10.7717/peerj.9120 PubMed 32714651
June 18, 2020
Structural analysis of leucine, lysine and tryptophan mitochondrial tRNA of nesting turtles Caretta caretta (Testudines: Chelonioidea) in the Colombian Caribbean
Harvey Infante-Rojas, Leonardo Marino-Ramirez, Javier Hernández-Fernández
https://doi.org/10.7717/peerj.9204 PubMed 32596037
June 5, 2020
Profiling lysophosphatidic acid levels in plasma from head and neck cancer patients
Mariati Abdul Rahman, Didi Erwandi Mohamad Haron, Robert J. Hollows, Zuleen Delina Fasya Abdul Ghani, Mustafa Ali Mohd, Wen Lin Chai, Ching Ching Ng, Munn Sann Lye, Saiful Anuar Karsani, Lee Fah Yap, Ian C. Paterson
https://doi.org/10.7717/peerj.9304 PubMed 32547888
June 3, 2020
Identification of DEGs and transcription factors involved in H. pylori-associated inflammation and their relevance with gastric cancer
Honghao Yin, Aining Chu, Songyi Liu, Yuan Yuan, Yuehua Gong
https://doi.org/10.7717/peerj.9223 PubMed 32547867
May 21, 2020
VIRdb: a comprehensive database for interactive analysis of genes/proteins involved in the pathogenesis of vitiligo
Priyansh Srivastava, Alakto Choudhury, Mehak Talwar, Sabyasachi Mohanty, Priyanka Narad, Abhishek Sengupta
https://doi.org/10.7717/peerj.9119 PubMed 32509450
May 20, 2020
Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A
Nuchsupha Sunthamala, Neeranuch Sankla, Jureeporn Chuerduangphui, Piyawut Swangphon, Wanchareeporn Boontun, Supakpong Ngaochaiyaphum, Weerayut Wongjampa, Tipaya Ekalaksananan, Chamsai Pientong
https://doi.org/10.7717/peerj.9213 PubMed 32509466
May 1, 2020
Enhancing flavonoid production by promiscuous activity of prenyltransferase, BrPT2 from Boesenbergia rotunda
Yvonne Jing Mei Liew, Yean Kee Lee, Norzulaani Khalid, Noorsaadah Abd Rahman, Boon Chin Tan
https://doi.org/10.7717/peerj.9094 PubMed 32391211
April 29, 2020
The predictive value of PRDM2 in solid tumor: a systematic review and meta-analysis
Caroline Tanadi, Alfredo Bambang, Indra Putra Wendi, Veronika M. Sidharta, Linawati Hananta, Anton Sumarpo
https://doi.org/10.7717/peerj.8826 PubMed 32391195
April 29, 2020
Aberrant expression of two miRNAs promotes proliferation, hepatitis B virus amplification, migration and invasion of hepatocellular carcinoma cells: evidence from bioinformatic analysis and experimental validation
Yanming Liu, Yue Cao, Wencan Cai, Liangyin Wu, Pingsen Zhao, Xin-guang Liu
https://doi.org/10.7717/peerj.9100 PubMed 32377460
April 23, 2020
Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus
José M. Viader-Salvadó, José Alberto Aguilar Briseño, Juan A. Gallegos-López, José A. Fuentes-Garibay, Carlos Alfonso Alvarez-González, Martha Guerrero-Olazarán
https://doi.org/10.7717/peerj.9030 PubMed 32351789
April 14, 2020
Accumulation of sequence variants in genes of Wnt signaling and focal adhesion pathways in human corneas further explains their involvement in keratoconus
Justyna A. Karolak, Tomasz Gambin, Malgorzata Rydzanicz, Piotr Polakowski, Rafal Ploski, Jacek P. Szaflik, Marzena Gajecka
https://doi.org/10.7717/peerj.8982 PubMed 32328353
April 14, 2020
Proteomic profiling analysis of postmenopausal osteoporosis and osteopenia identifies potential proteins associated with low bone mineral density
Dageng Huang, Yangyang Wang, Jing Lv, Yuzhu Yan, Ya Hu, Cuicui Liu, Feng Zhang, Jihan Wang, Dingjun Hao
https://doi.org/10.7717/peerj.9009 PubMed 32328356
March 31, 2020
Diagnostic model of combined ceRNA and DNA methylation related genes in esophageal carcinoma
Xiaojiao Guan, Yao Yao, Guangyao Bao, Yue Wang, Aimeng Zhang, Xinwen Zhong
https://doi.org/10.7717/peerj.8831 PubMed 32266120
March 30, 2020
Identification and functional characterization of a β-glucosidase from Bacillus tequelensis BD69 expressed in bacterial and yeast heterologous systems
Ahmad Raza, Ratnasri Pothula, Heba Abdelgaffar, Saira Bashir, Juan Luis Jurat-Fuentes
https://doi.org/10.7717/peerj.8792 PubMed 32266116
March 23, 2020
The heat shock protein family gene Hspa1l in male mice is dispensable for fertility
Xin Wang, Wenxiu Xie, Yejin Yao, Yunfei Zhu, Jianli Zhou, Yiqiang Cui, Xuejiang Guo, Yan Yuan, Zuomin Zhou, Mingxi Liu
https://doi.org/10.7717/peerj.8702 PubMed 32231871
March 12, 2020
In vitro anticancer activity of methanolic extract of Granulocystopsis sp., a microalgae from an oligotrophic oasis in the Chihuahuan desert
Faviola Tavares-Carreón, Susana De la Torre-Zavala, Hector Fernando Arocha-Garza, Valeria Souza, Luis J. Galán-Wong, Hamlet Avilés-Arnaut
https://doi.org/10.7717/peerj.8686 PubMed 32201642
March 10, 2020
Expanding the utility of the dextran sulfate sodium (DSS) mouse model to induce a clinically relevant loss of intestinal barrier function
Kyle E. Cochran, Nicholas G. Lamson, Kathryn A. Whitehead
https://doi.org/10.7717/peerj.8681 PubMed 32195049
March 9, 2020
Identification and validation of HELLS (Helicase, Lymphoid-Specific) and ICAM1 (Intercellular adhesion molecule 1) as potential diagnostic biomarkers of lung cancer
Wei Zhu, Lin Lin Li, Yiyan Songyang, Zhan Shi, Dejia Li
https://doi.org/10.7717/peerj.8731 PubMed 32195055
March 2, 2020
Expression patterns and the prognostic value of the EMILIN/Multimerin family members in low-grade glioma
Yonghui Zhao, Xiang Zhang, Junchao Yao, Zhibin Jin, Chen Liu
https://doi.org/10.7717/peerj.8696 PubMed 32175193
February 20, 2020
Single nucleotide polymorphism of MTHFR rs1801133 associated with elevated Hcy levels affects susceptibility to cerebral small vessel disease
Hongyu Yuan, Man Fu, Xianzhang Yang, Kun Huang, Xiaoyan Ren
https://doi.org/10.7717/peerj.8627 PubMed 32117640
February 14, 2020
Characterization of a Mn-SOD from the desert beetle Microdera punctipennis and its increased resistance to cold stress in E. coli cells
Zilajiguli Xikeranmu, Ji Ma, Xiaoning Liu
https://doi.org/10.7717/peerj.8507 PubMed 32095349
February 12, 2020
The effect of hepatopancreas homogenate of the Red king crab on HA-based filler
Tatyana Ponomareva, Dmitrii Sliadovskii, Maria Timchenko, Maxim Molchanov, Alexander Timchenko, Evgeny Sogorin
https://doi.org/10.7717/peerj.8579 PubMed 32095375
February 10, 2020
Downregulation of miR-193a-3p is involved in the pathogenesis of hepatocellular carcinoma by targeting CCND1
Shi-shuo Wang, Zhi-guang Huang, Hua-yu Wu, Rong-quan He, Li-hua Yang, Zhen-bo Feng, Yi-wu Dang, Hui-ping Lu, Ye-ying Fang, Gang Chen
https://doi.org/10.7717/peerj.8409 PubMed 32095323
February 7, 2020
Comparison of routine hematological indicators of liver and kidney function, blood count and lipid profile in healthy people and stroke patients
Xiaofang Cui, Wei Wei, Xiao Qin, Fei Hou, Jin Zhu, Weiyang Li
https://doi.org/10.7717/peerj.8545 PubMed 32071823
February 6, 2020
Postoperative hyperlactatemia and serum lactate level trends among heart transplant recipients
Anna Kędziora, Karol Wierzbicki, Jacek Piątek, Hubert Hymczak, Izabela Górkiewicz-Kot, Irena Milaniak, Paulina Tomsia, Dorota Sobczyk, Rafal Drwila, Boguslaw Kapelak
https://doi.org/10.7717/peerj.8334 PubMed 32071799
February 4, 2020
Identification and validation of key modules and hub genes associated with the pathological stage of oral squamous cell carcinoma by weighted gene co-expression network analysis
Xuegang Hu, Guanwen Sun, Zhiqiang Shi, Hui Ni, Shan Jiang
https://doi.org/10.7717/peerj.8505 PubMed 32117620
January 31, 2020
Protein expression profile changes of lung tissue in patients with pulmonary hypertension
Min Wu, Yijin Wu, Jinsong Huang, Yueheng Wu, Hongmei Wu, Benyuan Jiang, Jian Zhuang
https://doi.org/10.7717/peerj.8153 PubMed 32030316
January 21, 2020
Clinical characteristics and prognostic value of MEX3A mRNA in liver cancer
Dingquan Yang, Yan Jiao, Yanqing Li, Xuedong Fang
https://doi.org/10.7717/peerj.8252 PubMed 31998552
January 21, 2020
Inhibiting SLC26A4 reverses cardiac hypertrophy in H9C2 cells and in rats
Liqun Tang, Xiaoqin Yu, Yangyang Zheng, Ning Zhou
https://doi.org/10.7717/peerj.8253 PubMed 31998553
January 21, 2020
Differentially expressed genes and key molecules of BRCA1/2-mutant breast cancer: evidence from bioinformatics analyses
Yue Li, Xiaoyan Zhou, Jiali Liu, Yang Yin, Xiaohong Yuan, Ruihua Yang, Qi Wang, Jing Ji, Qian He
https://doi.org/10.7717/peerj.8403 PubMed 31998560
January 17, 2020
Autophagy-related genes prognosis signature as potential predictive markers for immunotherapy in hepatocellular carcinoma
Deli Mao, Zhe Zhang, Xin Zhao, Xiaoqiang Dong
https://doi.org/10.7717/peerj.8383 PubMed 31988807
January 7, 2020
Development of an autophagy-related gene prognostic signature in lung adenocarcinoma and lung squamous cell carcinoma
Jie Zhu, Min Wang, Daixing Hu
https://doi.org/10.7717/peerj.8288 PubMed 31938577
December 20, 2019
Reduced GRAMD1C expression correlates to poor prognosis and immune infiltrates in kidney renal clear cell carcinoma
Haiyan Hao, Ziheng Wang, Shiqi Ren, Hanyu Shen, Hua Xian, Wenliang Ge, Wei Wang
https://doi.org/10.7717/peerj.8205 PubMed 31875150
December 19, 2019
Biomarker potential of repetitive-element transcriptome in lung cancer
Macarena Arroyo, Rocío Bautista, Rafael Larrosa, Manuel Ángel Cobo, M. Gonzalo Claros
https://doi.org/10.7717/peerj.8277 PubMed 31875158
December 19, 2019
Identification of target genes in neuroinflammation and neurodegeneration after traumatic brain injury in rats
Jianwei Zhao, Chen Xu, Heli Cao, Lin Zhang, Xuyang Wang, Shiwen Chen
https://doi.org/10.7717/peerj.8324 PubMed 31875163
December 9, 2019
Systematic analysis and prediction model construction of alternative splicing events in hepatocellular carcinoma: a study on the basis of large-scale spliceseq data from The Cancer Genome Atlas
Lingpeng Yang, Yang He, Zifei Zhang, Wentao Wang
https://doi.org/10.7717/peerj.8245 PubMed 31844595
November 29, 2019
Screening and identification of key candidate genes and pathways in myelodysplastic syndrome by bioinformatic analysis
Ying Le
https://doi.org/10.7717/peerj.8162 PubMed 31803541
November 22, 2019
Molecular characterization of G-protein-coupled receptor (GPCR) and protein kinase A (PKA) cDNA in Perinereis aibuhitensis and expression during benzo(a)pyrene exposure
Yi Huang, Jia Sun, Ping Han, Heling Zhao, Mengting Wang, Yibing Zhou, Dazuo Yang, Huan Zhao
https://doi.org/10.7717/peerj.8044 PubMed 31772834
November 20, 2019
Transcriptional characterization and response to defense elicitors of mevalonate pathway genes in cotton (Gossypium arboreum L.)
Zhiqiang Zhang, Wei Liu, Zongbin Ma, Wei Zhu, Lin Jia
https://doi.org/10.7717/peerj.8123 PubMed 31768304
November 18, 2019
Angiogenic signaling in the lungs of a metabolically suppressed hibernating mammal (Ictidomys tridecemlineatus)
Samantha M. Logan, Kenneth B. Storey
https://doi.org/10.7717/peerj.8116 PubMed 31763078
November 13, 2019
First microsatellite markers for the pine catkin sawfly Xyela concava (Hymenoptera, Xyelidae) and their application in phylogeography and population genetics
Dustin Kulanek, Stephan M. Blank, Katja Kramp
https://doi.org/10.7717/peerj.8010 PubMed 31741792
November 11, 2019
Development of molecular markers for invasive alien plants in Korea: a case study of a noxious weed, Cenchrus longispinus (Hack.) Fernald, based on next generation sequencing data
JongYoung Hyun, Hoang Dang Khoa Do, Joonhyung Jung, Joo-Hwan Kim
https://doi.org/10.7717/peerj.7965 PubMed 31737445
November 4, 2019
MHC class I allele diversity in cynomolgus macaques of Vietnamese origin
Shuting Huang, Xia Huang, Shuang Li, Mingjun Zhu, Min Zhuo
https://doi.org/10.7717/peerj.7941 PubMed 31720104
November 1, 2019
Identification of key genes and long non-coding RNA associated ceRNA networks in hepatocellular carcinoma
Jun Liu, Wenli Li, Jian Zhang, Zhanzhong Ma, Xiaoyan Wu, Lirui Tang
https://doi.org/10.7717/peerj.8021 PubMed 31695969
October 31, 2019
A genomic-clinical nomogram predicting recurrence-free survival for patients diagnosed with hepatocellular carcinoma
Junjie Kong, Tao Wang, Shu Shen, Zifei Zhang, Xianwei Yang, Wentao Wang
https://doi.org/10.7717/peerj.7942 PubMed 31687273
October 17, 2019
Identification of key genes and multiple molecular pathways of metastatic process in prostate cancer
Lihuang Guo, Mingyue Lin, Zhenbo Cheng, Yi Chen, Yue Huang, Keqian Xu
https://doi.org/10.7717/peerj.7899 PubMed 31637138
October 7, 2019
CELSR3 mRNA expression is increased in hepatocellular carcinoma and indicates poor prognosis
Xuefeng Gu, Hongbo Li, Ling Sha, Yuan Mao, Chuanbing Shi, Wei Zhao
https://doi.org/10.7717/peerj.7816 PubMed 31608178
October 3, 2019
Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics
Garima Singh, Sri Krishna jayadev Magani, Rinku Sharma, Basharat Bhat, Ashish Shrivastava, Madhusudhan Chinthakindi, Ashutosh Singh
https://doi.org/10.7717/peerj.7425 PubMed 31592339
October 2, 2019
Increased expression of RUNX1 in clear cell renal cell carcinoma predicts poor prognosis
Yang Fu, Shanshan Sun, Xiaojun Man, Chuize Kong
https://doi.org/10.7717/peerj.7854 PubMed 31592165
October 1, 2019
CD36 identified by weighted gene co-expression network analysis as a hub candidate gene in lupus nephritis
Huiying Yang, Hua Li
https://doi.org/10.7717/peerj.7722 PubMed 31592160
September 27, 2019
Cytotoxic activity of IMMUNEPOTENT CRP against non-small cell lung cancer cell lines
Ana Carolina Martinez-Torres, Luis Gomez-Morales, Alan B. Martinez-Loria, Ashanti Concepcion Uscanga-Palomeque, Jose Manuel Vazquez-Guillen, Cristina Rodriguez-Padilla
https://doi.org/10.7717/peerj.7759 PubMed 31579619
September 26, 2019
Exploring the expression and preliminary function of chicken Gimap5 gene
Wanting Zhang, Sifan Xu, Guanxian Wu, Yang Liu, Qiuyuan Wang, Chaolai Man
https://doi.org/10.7717/peerj.7618 PubMed 31579581
September 20, 2019
Curcumin plays a synergistic role in combination with HSV-TK/GCV in inhibiting growth of murine B16 melanoma cells and melanoma xenografts
Hong Li, Haiyan Du, Guangxian Zhang, Yingya Wu, Pengxiang Qiu, Jingjing Liu, Jing Guo, Xijuan Liu, Lingling Sun, Biaoyan Du, Yuhui Tan
https://doi.org/10.7717/peerj.7760 PubMed 31579620
September 17, 2019
Liver slice culture as a model for lipid metabolism in fish
Thomas N. Harvey, Simen R. Sandve, Yang Jin, Jon Olav Vik, Jacob S. Torgersen
https://doi.org/10.7717/peerj.7732 PubMed 31576253
September 6, 2019
Identification of Flap endonuclease 1 as a potential core gene in hepatocellular carcinoma by integrated bioinformatics analysis
Chuanfei Li, Feng Qin, Hao Hong, Hui Tang, Xiaoling Jiang, Shuangyan Yang, Zhechuan Mei, Di Zhou
https://doi.org/10.7717/peerj.7619 PubMed 31534853
September 2, 2019
Proteomics and bioinformatics analysis reveal potential roles of cadmium-binding proteins in cadmium tolerance and accumulation of Enterobacter cloacae
Kitipong Chuanboon, Piyada Na Nakorn, Supitcha Pannengpetch, Vishuda Laengsri, Pornlada Nuchnoi, Chartchalerm Isarankura-Na-Ayudhya, Patcharee Isarankura-Na-Ayudhya
https://doi.org/10.7717/peerj.6904 PubMed 31534833
August 27, 2019
Insights from the proteome profile of Phytophthora capsici in response to the novel fungicide SYP-14288
Meng Cai, Zhiwen Wang, Xiaoxia Ni, Yanhua Hou, Qin Peng, Xiang Gao, Xili Liu
https://doi.org/10.7717/peerj.7626 PubMed 31523524
August 21, 2019
Genome-wide identification and expression analysis of the VQ gene family in soybean (Glycine max)
Yongbin Wang, Zhenfeng Jiang, Zhenxiang Li, Yuanling Zhao, Weiwei Tan, Zhaojun Liu, Shaobin Cui, Xiaoguang Yu, Jun Ma, Guangjin Wang, Wenbin Li
https://doi.org/10.7717/peerj.7509 PubMed 31497394
August 16, 2019
Exploring the potential of deep-blue autofluorescence for monitoring amyloid fibril formation and dissociation
Mantas Ziaunys, Tomas Sneideris, Vytautas Smirnovas
https://doi.org/10.7717/peerj.7554 PubMed 31440437
August 12, 2019
Phosphorylation/dephosphorylation response to light stimuli of Symbiodinium proteins: specific light-induced dephosphorylation of an HSP-like 75 kDa protein from S. microadriaticum
Raúl E. Castillo-Medina, Tania Islas-Flores, Marco A. Villanueva
https://doi.org/10.7717/peerj.7406 PubMed 31423357
July 25, 2019
Comprehensive map and functional annotation of the mouse white adipose tissue proteome
Xiaoyue Tang, Juan Li, Wei-gang Zhao, Haidan Sun, Zhengguang Guo, Li Jing, Zhufang She, Tao Yuan, Shuai-nan Liu, Quan Liu, Yong Fu, Wei Sun
https://doi.org/10.7717/peerj.7352 PubMed 31380149
July 10, 2019
Comparative transcriptomic and proteomic analyses of the green and white parts of chimeric leaves in Ananas comosus var. bracteatus
Yanbin Xue, Jun Ma, Yehua He, Sanmiao Yu, Zhen Lin, Yingyuan Xiong, Fatima Rafique, Fuxing Jiang, Lingxia Sun, Mingdong Ma, Yujue Zhou, Xi Li, Zhuo Huang
https://doi.org/10.7717/peerj.7261 PubMed 31333908
July 8, 2019
A proposed update for the classification and description of bacterial lipolytic enzymes
Thomas C.A. Hitch, Thomas Clavel
https://doi.org/10.7717/peerj.7249 PubMed 31328034
July 3, 2019
CRISPR/Cas9-mediated VDR knockout plays an essential role in the growth of dermal papilla cells through enhanced relative genes
Ye Gao, Miaohan Jin, Yiyuan Niu, Hailong Yan, Guangxian Zhou, Yulin Chen
https://doi.org/10.7717/peerj.7230 PubMed 31309000
July 2, 2019
Mitochondrial genomics of human pathogenic parasite Leishmania (Viannia) panamensis
Daniel Alfonso Urrea, Omar Triana-Chavez, Juan F. Alzate
https://doi.org/10.7717/peerj.7235 PubMed 31304069
June 24, 2019
Expression of osteopontin, matrix metalloproteinase-2 and -9 proteins in vascular instability in brain arteriovenous malformation
Lalita Anbarasen, Jasmine Lim, Retnagowri Rajandram, Kein Seong Mun, Sheau Fung Sia
https://doi.org/10.7717/peerj.7058 PubMed 31275742
June 20, 2019
Proteomic identification of membrane-associated placental protein 4 (MP4) as perlecan and characterization of its placental expression in normal and pathologic pregnancies
Nikolett Lilla Szenasi, Eszter Toth, Andrea Balogh, Kata Juhasz, Katalin Karaszi, Oliver Ozohanics, Zsolt Gelencser, Peter Kiraly, Beata Hargitai, Laszlo Drahos, Petronella Hupuczi, Ilona Kovalszky, Zoltan Papp, Nandor Gabor Than
https://doi.org/10.7717/peerj.6982 PubMed 31259093
June 12, 2019
Investigation of the protein profile of silkworm (Bombyx mori) pupae reared on a well-calibrated artificial diet compared to mulberry leaf diet
Cristina Lamberti, Francesco Gai, Simona Cirrincione, Marzia Giribaldi, Micol Purrotti, Marcello Manfredi, Emilio Marengo, Benedetto Sicuro, Alessio Saviane, Silvia Cappellozza, Maria Gabriella Giuffrida, Laura Cavallarin
https://doi.org/10.7717/peerj.6723 PubMed 31223520
June 11, 2019
The role of acetyl-coA carboxylase2 in head and neck squamous cell carcinoma
Kun Li, Chengcheng Zhang, Lei Chen, Pingping Wang, Yang Fang, Junwei Zhu, Shuo Chen, Juan Du, Bing Shen, Kaile Wu, Yehai Liu
https://doi.org/10.7717/peerj.7037 PubMed 31218122
June 11, 2019
PGM5: a novel diagnostic and prognostic biomarker for liver cancer
Yan Jiao, Yanqing Li, Peiqiang Jiang, Wei Han, Yahui Liu
https://doi.org/10.7717/peerj.7070 PubMed 31218127
June 10, 2019
Age-related kinematic performance should be considered during fast head-neck rotation target task in individuals aged from 8 to 85 years old
Renaud Hage, Frédéric Dierick, Nathalie Roussel, Laurent Pitance, Christine Detrembleur
https://doi.org/10.7717/peerj.7095 PubMed 31218133
June 7, 2019
Chronic intake of high-dose of blueberry leaf extract does not augment the harmful effects of ethanol in rats
Kaede Yamasaki, Kazuhiro Sugamoto, Teruaki Arakawa, Kazuo Nishiyama, Masao Yamasaki
https://doi.org/10.7717/peerj.6989 PubMed 31211011
June 6, 2019
Integrative analysis of common genes and driver mutations implicated in hormone stimulation for four cancers in women
Salma Begum Bhyan, YongKiat Wee, Yining Liu, Scott Cummins, Min Zhao
https://doi.org/10.7717/peerj.6872 PubMed 31205821
May 31, 2019
Accelerated construction of an in vitro model of human periodontal ligament tissue: vacuum plasma combined with fibronectin coating and a polydimethylsiloxane matrix
Wen Liao, Yoshiya Hashimoto, Yoshitomo Honda, Peiqi Li, Yang Yao, Zhihe Zhao, Naoyuki Matsumoto
https://doi.org/10.7717/peerj.7036 PubMed 31183259
May 31, 2019
Resilience of BST-2/Tetherin structure to single amino acid substitutions
Ian R. Roy, Camden K. Sutton, Christopher E. Berndsen
https://doi.org/10.7717/peerj.7043 PubMed 31183261
May 21, 2019
Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads
Ilchan Song, Yang Joo Kang, Su-Lim Choi, Dalmuri Han, Deuk-Su Kim, Hae Kyung Lee, Joon-Chul Lee, Jeanho Park, Do-Sun Kim, Kisung Ko
https://doi.org/10.7717/peerj.6828 PubMed 31149395
May 21, 2019
Enzyme characterization and biological activities of a resuscitation promoting factor from an oil degrading bacterium Rhodococcus erythropolis KB1
Dan Luo, Jixiang Chen, Gang Xie, Liang Yue, Yonggang Wang
https://doi.org/10.7717/peerj.6951 PubMed 31149404
May 17, 2019
Cmah deficiency may lead to age-related hearing loss by influencing miRNA-PPAR mediated signaling pathway
Juhong Zhang, Na Wang, Anting Xu
https://doi.org/10.7717/peerj.6856 PubMed 31149396
April 26, 2019
OsteoporosAtlas: a human osteoporosis-related gene database
Xun Wang, Lihong Diao, Dezhi Sun, Dan Wang, Jiarun Zhu, Yangzhige He, Yuan Liu, Hao Xu, Yi Zhang, Jinying Liu, Yan Wang, Fuchu He, Yang Li, Dong Li
https://doi.org/10.7717/peerj.6778 PubMed 31086734
April 23, 2019
Identification of optimal endogenous reference RNAs for RT-qPCR normalization in hindgut of rat models with anorectal malformations
Caiyun Long, Yunxia Xiao, Siying Li, Xiaobing Tang, Zhengwei Yuan, Yuzuo Bai
https://doi.org/10.7717/peerj.6829 PubMed 31065464
April 16, 2019
Identification and expression analysis of the GDSL esterase/lipase family genes, and the characterization of SaGLIP8 in Sedum alfredii Hance under cadmium stress
He Li, Xiaojiao Han, Wenmin Qiu, Dong Xu, Ying Wang, Miao Yu, Xianqi Hu, Renying Zhuo
https://doi.org/10.7717/peerj.6741 PubMed 31024765
April 12, 2019
Adaptive and degenerative evolution of the S-Phase Kinase-Associated Protein 1-Like family in Arabidopsis thaliana
Zhihua Hua, Zhenyu Gao
https://doi.org/10.7717/peerj.6740 PubMed 30997292
April 2, 2019
Environmental modulation of the proteomic profiles from closely phylogenetically related populations of the red seaweed Plocamium brasiliense
Gabriela Calegario, Lucas Freitas, Eidy Santos, Bruno Silva, Louisi Oliveira, Gizele Garcia, Cláudia Omachi, Renato Pereira, Cristiane Thompson, Fabiano Thompson
https://doi.org/10.7717/peerj.6469 PubMed 30972241
March 22, 2019
Identification of key genes, pathways and potential therapeutic agents for liver fibrosis using an integrated bioinformatics analysis
Zhu Zhan, Yuhe Chen, Yuanqin Duan, Lin Li, Kenley Mew, Peng Hu, Hong Ren, Mingli Peng
https://doi.org/10.7717/peerj.6645 PubMed 30923657
March 21, 2019
Comparative analysis of the liver transcriptome in the red-eared slider Trachemys scripta elegans under chronic salinity stress
Meiling Hong, Aiping Jiang, Na Li, Weihao Li, Haitao Shi, Kenneth B. Storey, Li Ding
https://doi.org/10.7717/peerj.6538 PubMed 30923649
March 1, 2019
Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma
Neeraja M. Krishnan, Hiroto Katoh, Vinayak Palve, Manisha Pareek, Reiko Sato, Shumpei Ishikawa, Binay Panda
https://doi.org/10.7717/peerj.6464 PubMed 30842898
February 25, 2019
Emergence of visible light optical properties of L-phenylalanine aggregates
Mantas Ziaunys, Vytautas Smirnovas
https://doi.org/10.7717/peerj.6518 PubMed 30828498
February 19, 2019
Mulberry EIL3 confers salt and drought tolerances and modulates ethylene biosynthetic gene expression
Changying Liu, Jun Li, Panpan Zhu, Jian Yu, Jiamin Hou, Chuanhong Wang, Dingpei Long, Maode Yu, Aichun Zhao
https://doi.org/10.7717/peerj.6391 PubMed 30809434
February 19, 2019
Hybrid identification for Glycine max and Glycine soja with SSR markers and analysis of salt tolerance
Fayuan Li, Xun Liu, Shengyan Wu, Qingyun Luo, Bingjun Yu
https://doi.org/10.7717/peerj.6483 PubMed 30809456
February 6, 2019
Snake venom NAD glycohydrolases: primary structures, genomic location, and gene structure
Ivan Koludarov, Steven D. Aird
https://doi.org/10.7717/peerj.6154 PubMed 30755823
February 1, 2019
Genes of the pig, Sus scrofa, reconstructed with EvidentialGene
Donald G. Gilbert
https://doi.org/10.7717/peerj.6374 PubMed 30723633
January 9, 2019
Didymin improves UV irradiation resistance in C. elegans
Lin Zhou, Lu Wang, Jialing Zhang, Jiahe Li, Shuju Bai, Junfeng Ma, Xueqi Fu
https://doi.org/10.7717/peerj.6218 PubMed 30643686
December 11, 2018
Plant-derived chimeric antibodies inhibit the invasion of human fibroblasts by Toxoplasma gondii
Sherene Swee Yin Lim, Kek Heng Chua, Greta Nölke, Holger Spiegel, Wai Leong Goh, Sek Chuen Chow, Boon Pin Kee, Rainer Fischer, Stefan Schillberg, Rofina Yasmin Othman
https://doi.org/10.7717/peerj.5780 PubMed 30581655
December 7, 2018
In silico analyses for potential key genes associated with gastric cancer
Ping Yan, Yingchun He, Kexin Xie, Shan Kong, Weidong Zhao
https://doi.org/10.7717/peerj.6092 PubMed 30568862
November 16, 2018
Enhancement of a protocol purifying T1 lipase through molecular approach
Che Haznie Ayu Che Hussian, Raja Noor Zaliha Raja Abd. Rahman, Adam Leow Thean Chor, Abu Bakar Salleh, Mohd Shukuri Mohamad Ali
https://doi.org/10.7717/peerj.5833 PubMed 30479887
October 31, 2018
High-level expression and molecular characterization of a recombinant prolidase from Escherichia coli NovaBlue
Tzu-Fan Wang, Meng-Chun Chi, Kuan-Ling Lai, Min-Guan Lin, Yi-Yu Chen, Huei-Fen Lo, Long-Liu Lin
https://doi.org/10.7717/peerj.5863 PubMed 30402354
October 23, 2018
Molecular characterization of the giant freshwater prawn (Macrobrachium rosenbergii) beta-actin gene promoter
Junjun Yan, Qiang Gao, Zongbin Cui, Guoliang Yang, Yong Long
https://doi.org/10.7717/peerj.5701 PubMed 30386688
October 17, 2018
C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor
Shalini Iyer, Vasanta Subramanian, K. Ravi Acharya
https://doi.org/10.7717/peerj.5815 PubMed 30356970
October 16, 2018
The BackMAP Python module: how a simpler Ramachandran number can simplify the life of a protein simulator
Ranjan Mannige
https://doi.org/10.7717/peerj.5745 PubMed 30356937
October 5, 2018
Assessment of genomic changes in a CRISPR/Cas9 Phaeodactylum tricornutum mutant through whole genome resequencing
Monia Teresa Russo, Riccardo Aiese Cigliano, Walter Sanseverino, Maria Immacolata Ferrante
https://doi.org/10.7717/peerj.5507 PubMed 30310734
September 28, 2018
Crystal structure and functional analysis of human C1ORF123
Siti Nurulnabila A. Rahaman, Jastina Mat Yusop, Zeti-Azura Mohamed-Hussein, Wan Mohd Aizat, Kok Lian Ho, Aik-Hong Teh, Jitka Waterman, Boon Keat Tan, Hwei Ling Tan, Adelicia Yongling Li, Ee Sin Chen, Chyan Leong Ng
https://doi.org/10.7717/peerj.5377 PubMed 30280012
September 26, 2018
Tumor-preventing activity of aspirin in multiple cancers based on bioinformatic analyses
Diangeng Li, Peng Wang, Yi Yu, Bing Huang, Xuelin Zhang, Chou Xu, Xian Zhao, Zhiwei Yin, Zheng He, Meiling Jin, Changting Liu
https://doi.org/10.7717/peerj.5667 PubMed 30280037
September 19, 2018
Transkingdom network reveals bacterial players associated with cervical cancer gene expression program
Khiem Chi Lam, Dariia Vyshenska, Jialu Hu, Richard Rosario Rodrigues, Anja Nilsen, Ryszard A. Zielke, Nicholas Samuel Brown, Eva-Katrine Aarnes, Aleksandra E. Sikora, Natalia Shulzhenko, Heidi Lyng, Andrey Morgun
https://doi.org/10.7717/peerj.5590 PubMed 30294508
September 14, 2018
Luciferin production and luciferase transcription in the bioluminescent copepod Metridia lucens
Michael Tessler, Jean P. Gaffney, Jason M. Crawford, Eric Trautman, Nehaben A. Gujarati, Philip Alatalo, Vincent A. Pieribone, David F. Gruber
https://doi.org/10.7717/peerj.5506 PubMed 30233994
September 5, 2018
Identification of candidate genes and proteins in aging skeletal muscle (sarcopenia) using gene expression and structural analysis
Gita Shafiee, Yazdan Asgari, Akbar Soltani, Bagher Larijani, Ramin Heshmat
https://doi.org/10.7717/peerj.5239 PubMed 30202641
August 13, 2018
A novel long non-coding RNA, AC012456.4, as a valuable and independent prognostic biomarker of survival in oral squamous cell carcinoma
Xuegang Hu, Zailing Qiu, Jianchai Zeng, Tingting Xiao, Zhihong Ke, Hongbing Lyu
https://doi.org/10.7717/peerj.5307 PubMed 30128179
July 30, 2018
Genome-wide analysis reveals four key transcription factors associated with cadmium stress in creeping bentgrass (Agrostis stolonifera L.)
Jianbo Yuan, Yuqing Bai, Yuehui Chao, Xinbo Sun, Chunyan He, Xiaohong Liang, Lijuan Xie, Liebao Han
https://doi.org/10.7717/peerj.5191 PubMed 30083437
July 26, 2018
An automated identification and analysis of ontological terms in gastrointestinal diseases and nutrition-related literature provides useful insights
Orges Koci, Michael Logan, Vaios Svolos, Richard K. Russell, Konstantinos Gerasimidis, Umer Zeeshan Ijaz
https://doi.org/10.7717/peerj.5047 PubMed 30065857
July 4, 2018
Crystal structure of human Acinus RNA recognition motif domain
Humberto Fernandes, Honorata Czapinska, Katarzyna Grudziaz, Janusz M. Bujnicki, Martyna Nowacka
https://doi.org/10.7717/peerj.5163 PubMed 30042883
June 19, 2018
Comprehensive analysis of mitogen-activated protein kinase cascades in chrysanthemum
Aiping Song, Yueheng Hu, Lian Ding, Xue Zhang, Peiling Li, Ye Liu, Fadi Chen
https://doi.org/10.7717/peerj.5037 PubMed 29942696
June 18, 2018
Intein-mediated backbone cyclization of entolimod confers enhanced radioprotective activity in mouse models
Bingyu Ye, Wenlong Shen, Minglei Shi, Yan Zhang, Cunshuan Xu, Zhihu Zhao
https://doi.org/10.7717/peerj.5043 PubMed 29938138
June 15, 2018
A novel thymidylate synthase from the Vibrionales, Alteromonadales, Aeromonadales, and Pasteurellales (VAAP) clade with altered nucleotide and folate binding sites
Alonso A. Lopez-Zavala, Eduardo Guevara-Hernandez, Luz H. Vazquez-Lujan, Arturo Sanchez-Paz, Karina D. Garcia-Orozco, Carmen A. Contreras-Vergara, Gamaliel Lopez-Leal, Aldo A. Arvizu-Flores, Adrian Ochoa-Leyva, Rogerio R. Sotelo-Mundo
https://doi.org/10.7717/peerj.5023 PubMed 29922516
June 14, 2018
Structural insights and characterization of human Npas4 protein
Ammad Fahim, Zaira Rehman, Muhammad Faraz Bhatti, Amjad Ali, Nasar Virk, Amir Rashid, Rehan Zafar Paracha
https://doi.org/10.7717/peerj.4978 PubMed 29915698
June 5, 2018
Molecular attributes and apoptosis-inducing activities of a putative serine protease isolated from Tiger Milk mushroom (Lignosus rhinocerus) sclerotium against breast cancer cells in vitro
Hui Yeng Y. Yap, Nget Hong Tan, Szu Ting Ng, Chon Seng Tan, Shin Yee Fung
https://doi.org/10.7717/peerj.4940 PubMed 29888137
June 5, 2018
Discovery of digestive enzymes in carnivorous plants with focus on proteases
Rishiesvari Ravee, Faris ‘Imadi Mohd Salleh, Hoe-Han Goh
https://doi.org/10.7717/peerj.4914 PubMed 29888132
June 4, 2018
Pro-inflammatory AGE-RAGE signaling is activated during arousal from hibernation in ground squirrel adipose
Samantha M. Logan, Kenneth B. Storey
https://doi.org/10.7717/peerj.4911 PubMed 29888131
May 28, 2018
Antioxidant status of rats’ blood and liver affected by sodium selenite and selenium nanoparticles
Lenka Urbankova, Pavel Horky, Jiri Skladanka, Magdalena Pribilova, Vendula Smolikova, Pavel Nevrkla, Natalia Cernei, Zuzana Lackova, Josef Hedbavny, Andrea Ridoskova, Vojtech Adam, Pavel Kopel
https://doi.org/10.7717/peerj.4862 PubMed 29868274
May 22, 2018
Molecular response of canola to salt stress: insights on tolerance mechanisms
Reza Shokri-Gharelo, Pouya Motie Noparvar
https://doi.org/10.7717/peerj.4822 PubMed 29844974
April 25, 2018
Increased chemical acetylation of peptides and proteins in rats after daily ingestion of diacetyl analyzed by Nano-LC-MS/MS
Leticia Dias Lima Jedlicka, Sheila Barreto Guterres, Aleksandro Martins Balbino, Giuseppe Bruno Neto, Richardt Gama Landgraf, Liliam Fernandes, Emanuel Carrilho, Etelvino José Henriques Bechara, Nilson A. Assuncao
https://doi.org/10.7717/peerj.4688 PubMed 29713565
April 23, 2018
Genome comparison implies the role of Wsm2 in membrane trafficking and protein degradation
Guorong Zhang, Zhihua Hua
https://doi.org/10.7717/peerj.4678 PubMed 29707435
March 21, 2018
High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA
Jonathan R. Davies, Gavin S. Hackett, Sai Man Liu, K. Ravi Acharya
https://doi.org/10.7717/peerj.4552 PubMed 29576992
March 12, 2018
Molecular cloning and expression analysis of three ThERFs involved in the response to waterlogging stress of Taxodium ‘Zhongshanshan406’, and subcellular localization of the gene products
Wencai Fan, Ying Yang, Zhiquan Wang, Yunlong Yin, Chaoguang Yu, Qin Shi, Jinbo Guo, Lei Xuan, Jianfeng Hua
https://doi.org/10.7717/peerj.4434 PubMed 29576943
March 6, 2018
Cellular prion protein and γ-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch
Sing-Hui Ong, Kai-Wey Goh, Cornelius Kwang-Lee Chieng, Yee-How Say
https://doi.org/10.7717/peerj.4506 PubMed 29527422
December 5, 2017
Comparative analyses of putative toxin gene homologs from an Old World viper, Daboia russelii
Neeraja M. Krishnan, Binay Panda
https://doi.org/10.7717/peerj.4104 PubMed 29230357
November 9, 2017
The role of MEF2 transcription factors in dehydration and anoxia survival in Rana sylvatica skeletal muscle
Myriam P. Hoyeck, Hanane Hadj-Moussa, Kenneth B. Storey
https://doi.org/10.7717/peerj.4014 PubMed 29134152
July 7, 2017
Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3
Lila Yang, Maria Hansen Falkesgaard, Peter Waaben Thulstrup, Peter Schledermann Walmod, Leila Lo Leggio, Kim Krighaar Rasmussen
https://doi.org/10.7717/peerj.3550 PubMed 28698826
June 28, 2017
In-silico prediction and modeling of the Entamoeba histolytica proteins: Serine-rich Entamoeba histolytica protein and 29 kDa Cysteine-rich protease
Kumar Manochitra, Subhash Chandra Parija
https://doi.org/10.7717/peerj.3160 PubMed 28674640
March 30, 2017
Comparative proteomics of Rhizopus delemar ATCC 20344 unravels the role of amino acid catabolism in fumarate accumulation
Dorett I. Odoni, Juan A. Tamayo-Ramos, Jasper Sloothaak, Ruben G.A. van Heck, Vitor A.P. Martins dos Santos, Leo H. de Graaff, Maria Suarez-Diez, Peter J. Schaap
https://doi.org/10.7717/peerj.3133 PubMed 28382234
March 14, 2017
Computer modelling reveals new conformers of the ATP binding loop of Na+/K+-ATPase involved in the transphosphorylation process of the sodium pump
Gracian Tejral, Bruno Sopko, Alois Necas, Wilhelm Schoner, Evzen Amler
https://doi.org/10.7717/peerj.3087 PubMed 28316890
November 9, 2016
Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein
Theo Luiz Ferraz de Souza, Sheila Maria Barbosa de Lima, Vanessa L. de Azevedo Braga, David S. Peabody, Davis Fernandes Ferreira, M. Lucia Bianconi, Andre Marco de Oliveira Gomes, Jerson Lima Silva, Andréa Cheble de Oliveira
https://doi.org/10.7717/peerj.2670 PubMed 27867765
July 20, 2016
Proteomic indicators of oxidation and hydration state in colorectal cancer
Jeffrey M. Dick
https://doi.org/10.7717/peerj.2238 PubMed 27547546
February 25, 2016
Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases
Wouter Boomsma, Sofie V. Nielsen, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen, Lars Ellgaard
https://doi.org/10.7717/peerj.1725 PubMed 26966660
February 4, 2016
Identification of fibrillogenic regions in human triosephosphate isomerase
Edson N. Carcamo-Noriega, Gloria Saab-Rincon
https://doi.org/10.7717/peerj.1676 PubMed 26870617
January 4, 2016
The yeast telomerase RNA, TLC1, participates in two distinct modes of TLC1-TLC1 association processes in vivo
Tet Matsuguchi, Elizabeth Blackburn
https://doi.org/10.7717/peerj.1534 PubMed 27004145
October 1, 2015
Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cells
Nurhanani Razali, Azlina Abdul Aziz, Chor Yin Lim, Sarni Mat Junit
https://doi.org/10.7717/peerj.1292 PubMed 26557426
August 20, 2015
Polymorphism of amyloid-like fibrils can be defined by the concentration of seeds
Tomas Sneideris, Katažyna Milto, Vytautas Smirnovas
https://doi.org/10.7717/peerj.1207 PubMed 26355941
June 30, 2015
The destructive effect of botulinum neurotoxins on the SNARE protein: SNAP-25 and synaptic membrane fusion
Bin Lu
https://doi.org/10.7717/peerj.1065 PubMed 26157630
May 12, 2015
The diversity of membrane transporters encoded in bacterial arsenic-resistance operons
Yiren Yang, Shiyang Wu, Ross McCausland Lilley, Ren Zhang
https://doi.org/10.7717/peerj.943 PubMed 26020003
May 7, 2015
Calcium affinity of human α-actinin 1
Lars Backman
https://doi.org/10.7717/peerj.944 PubMed 26020004
January 8, 2015
Association between intrinsic disorder and serine/threonine phosphorylation in Mycobacterium tuberculosis
Gajinder Pal Singh
https://doi.org/10.7717/peerj.724 PubMed 25648268
October 28, 2014
Purification and properties of glyceraldehyde-3-phosphate dehydrogenase from the skeletal muscle of the hibernating ground squirrel, Ictidomys tridecemlineatus
Ryan A.V. Bell, Jeffrey C. Smith, Kenneth B. Storey
https://doi.org/10.7717/peerj.634 PubMed 25374779
August 5, 2014
Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis
Chelsea N. Laatsch, Blythe P. Durbin-Johnson, David M. Rocke, Sophie Mukwana, Abby B. Newland, Michael J. Flagler, Michael G. Davis, Richard A. Eigenheer, Brett S. Phinney, Robert H. Rice
https://doi.org/10.7717/peerj.506 PubMed 25165623
August 5, 2014
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