Timothy M Ryan

PeerJ Author

Summary

BSc (hons) from the University of Melbourne majoring in Biochemistry, followed by a PhD in biochemistry studying the aggregation of apolipoproteins into amyloid fibrils. Currently a post doc studying the toxic principle of Alzheimer's disease.

Biochemistry Biophysics Biotechnology Neuroscience

Editing Journals

Work details

Beamline Scientist

Australian Synchrotron

SAXS/WAXS

May 7, 2013

Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization

Timothy M. Ryan, Joanne Caine, Haydyn D.T. Mertens, Nigel Kirby, Julie Nigro, Kerry Breheney, Lynne J. Waddington, Victor A. Streltsov, Cyril Curtain, Colin L. Masters, Blaine R. Roberts

https://doi.org/10.7717/peerj.73 PubMed 23678397

7 Answers

accepted Amyloid beta lyophilization

i wanna make amyloid beta 42 as oligomers

accepted How did you arrive at a 10+5 min incubation?

I wanna make amyloid beta 42 as a monomer.

I can't make amyloid beta 42 as a powder form

accepted My amyloid beta doesn't dissolve

How to generate small toxic oligomers in vitro?