Academic Editor

Erich M Schwarz


Summary

Research Scientist in Molecular Biology and Genetics, Cornell Univ.; Honorary Research Fellow in Veterinary Science, Univ. of Melbourne.

I use comparative nematode genomics and RNA-seq analysis to decipher both parasitic disease and fundamental biology. To identify genes that encode possible vaccine targets, I have sequenced and analyzed the genomes and transcriptomes of two major parasitic nematodes, and compared them both to one another and to related non-parasitic nematodes. To identify genes that enable males and females in a species to reproduce, I am currently comparing genomes of hermaphroditic Caenorhabditis species to genomes of closely related gonochoristic (male-female) species, and looking for gene families that have been partially or completely lost in self-fertilizing hermaphrodites. To identify gene functions relevant to core metazoan biology, I am identifying genes conserved between C. elegans and humans that are largely or completely uncharacterized ("conserved unknowns"), which my collaborators are testing for function in vivo.

Bioinformatics Computational Biology Genetics Genomics Molecular Biology Parasitology

Institution affiliations

Work details

Research Scientist

Cornell University
January 2012
Department of Molecular Biology and Genetics
Equivalent to Research Assistant Professor; full-time academic research without teaching duties.

Associate Biologist

California Institute of Technology
March 2000 - December 2012
Division of Biology and Biological Engineering
Senior researcher working in the laboratory of Paul Sternberg on WormBase and nematode genomics.

Websites

PeerJ Contributions