Patrick A Lewis

Summary

My research is focused on understanding the molecular pathways that lead to inherited Parkinson's disease linked to mutations in Leucine rich repeat kinase 2 (LRRK2). Mutations in this gene are the single most common genetic cause of Parkinson's disease, affecting 5-10,000 people in the UK alone. My lab is investigating how these mutations alter cellular function and fate, with a particular interest in macroautophagy and lysosomal biology.

Biochemistry Neuroscience

Institution affiliations