My name is Huizhan Liu, and I graduated from medical school in 2008. And then I worked in the Institute of Otolaryngology, Chinese PLA General Hospital. In 2012, I joined into Dr David’s lab, in Biomedical Science Department of Creighton University, Omaha, NE. My research efforts have been focused on the genetics, pathology and molecular biological mechanisms of several major groups of sensorineural hearing loss. My current experiments are about studying the mechanisms of the inner ear’s outer hair cell (OHC), which is a kind of receptor cells and plays a critical role in mammalian hearing. OHCs enhance basilar membrane motion through a local mechanical feedback process within the cochlea, termed the ‘cochlear amplifier’. The research in my laboratory focuses on the forward and reverse transduction in OHCs. Recordings are made from isolated hair cells, cultured organ of Corti preparations, and hemicochlea, in conjunction with molecular, morphological and other novel techniques to investigate properties of these cells and their roles in cochlear functions in mammals. The laboratory is fully equipped to conduct experiments at the cellular level with novel techniques. It includes three setups for doing standard whole-cell patch-clamp experiments. All three setups are also equipped with opto-electronic systems that allow measuring cell/hair-bundle motion down to nanometer range.