WANT A PROFILE LIKE THIS?
Create my FREE Plan Or learn about other options
Elizabeth Laird
PeerJ Editor
100 Points

Contributions by role

Editor 100

Contributions by subject area

Cell Biology
Orthopedics
Rheumatology
Translational Medicine

Elizabeth G. Laird

PeerJ Editor

Summary

My research goals are to characterise the mechanisms of collagenous tissue development, repair and renewal. Current research interests include understanding the dynamics of collagen synthesis and turnover, the role of stem cells in musculoskeletal homeostasis and the role of glucose in musculoskeletal ageing. Tissues of interest are primarily tendon and ligament but include cartilage, bone, cornea and intervertebral disc, as well as fibrotic tissue.

This research is important because age-related degeneration and loss of function in musculoskeletal tissues is associated with chronic joint pain, limited movement, tendinopathy, ligament damage, intervertebral disc degeneration and osteoarthritis. There is both a loss of tissue integrity and propensity to fibrosis indicating that homeostasis of the collagenous extracellular matrix is lost with age. Understanding the molecular processes that create functional musculoskeletal tissues during development and growth, and which malfunction or cease to operate in aged tissues is key to developing new strategies for tissue engineering, to activate intrinsic stem cell repair mechanisms and to develop beneficial pharmaceutical, dietary or exercise-based interventions in an increasingly aged society.

Biochemistry Cell Biology Developmental Biology Molecular Biology Rheumatology

Editorial Board Member

PeerJ - the Journal of Life & Environmental Sciences

Past or current institution affiliations

University of Liverpool

Work details

Reader

University of Liverpool
Department of Musculoskeletal Biology

Websites

  • PubMed Search
  • Researchgate
  • University Profile

PeerJ Contributions