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David Meyre
PeerJ Editor & Author
1,370 Points

Contributions by role

Author 235
Editor 1,135

Contributions by subject area

Genetics
Diabetes and Endocrinology
Cardiology
Pediatrics
Gynecology and Obstetrics
Women's Health
Medical Genetics
Gastroenterology and Hepatology
Nutrition
Psychiatry and Psychology
Surgery and Surgical Specialties
Public Health
Computational Science
Health Policy
Statistics
Epidemiology
Neurology
Bioinformatics
Genomics
Allergy and Clinical Immunology
Rheumatology

David Meyre

PeerJ Editor & Author

Summary

David Meyre completed a PhD in quantitative plant genetics in France. Since 2001, he has been working on the elucidation of the genetic bases of obesity and type 2 diabetes. In 2004, he published the first family-based genome-wide scans for childhood and severe adult obesity. He completed the two first successful positional cloning efforts for childhood and severe adult obesity, which identified the positional candidate genes ENPP1 and PCSK1. In 2007, he contributed to the identification of the major susceptibility gene for polygenic obesity FTO. In 2009, he published the first genome-wide association study of extreme obesity in the French population and identified four novel susceptibility-loci. In 2010, he conducted the first genome-wide association meta-analysis for early-onset extreme obesity in German and French populations. In 2012, he identified the third more common form of monogenic obesity (PCSK1 partial deficiency) and demonstrated an important role of the lipid sensor GPR120 in human obesity. He also discovered the first molecular link between obesity and major depression. In 2013, he discovered a novel gene (SIM1) responsible for a syndromic Mendelian form of childhood obesity. In 2016, he discovered that physical activity can blunt the effect of the obesity predisposing gene FTO in diverse ethnic groups. He also demonstrated that genes can predict the outcomes of different types of bariatric surgery.

Diabetes & Endocrinology Genetics Genomics Nutrition Obesity Statistics

Editing Journals

PeerJ - the Journal of Life & Environmental Sciences

Past or current institution affiliations

McMaster University

Work details

Associate Professor

McMaster University
Department of Clinical Epidemiology & Biostatistics
With 164 articles published up to date (94 appeared in top-tier journals including Nature, Science, Nature Genetics...), 17,400 citations and a H-index of 53, Dr Meyre is an international expert in genetic epidemiology of obesity and type 2 diabetes. Dr Meyre is developing a multidisciplinary obesity genetic research program at McMaster University to provide an exhaustive picture of the etiology of this complex disorder and to equip the decision makers with the appropriate tools in order to tackle obesity and its complications worldwide. His current research interests include 1) gene identification in diverse ethnic groups 2) gene x environment interactions 3) epigenetics 4) evolutionary genetics 5) molecular physiology 6) systems biology 7) development of new methods and guidelines 8) knowledge synthesis 9) knowledge translation and 10) evidence-based personalized prevention and medicine.

Websites

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PeerJ Contributions

  • Articles 2
  • Edited 11
June 23, 2016
Genetic markers of inflammation may not contribute to metabolic traits in Mexican children
Neeti Vashi, Carolina Stryjecki, Jesus Peralta-Romero, Fernando Suarez, Jaime Gomez-Zamudio, Ana I. Burguete-Garcia, Miguel Cruz, David Meyre
https://doi.org/10.7717/peerj.2090 PubMed 27366637
March 24, 2015
Obesity genetics in mouse and human: back and forth, and back again
Fereshteh T. Yazdi, Susanne M. Clee, David Meyre
https://doi.org/10.7717/peerj.856 PubMed 25825681

Academic Editor on

January 15, 2020
Genetic architecture study of rheumatoid arthritis and juvenile idiopathic arthritis
Jun Jia, Junyi Li, Xueming Yao, YuHang Zhang, Xiaohao Yang, Ping Wang, Qianghua Xia, Hakon Hakonarson, Jin Li
https://doi.org/10.7717/peerj.8234 PubMed 31988799
May 3, 2018
Relationships between parents’ academic backgrounds and incomes and building students’ healthy eating habits
Kazi Enamul Hoque, Kazi Fardinul Hoque, Revethy A/P Thanabalan
https://doi.org/10.7717/peerj.4563 PubMed 29736328
March 16, 2018
The use of nutritional supplements to induce ketosis and reduce symptoms associated with keto-induction: a narrative review
Cliff J. d C. Harvey, Grant M. Schofield, Micalla Williden
https://doi.org/10.7717/peerj.4488 PubMed 29576959
July 13, 2017
Association of polymorphic markers of genes FTO, KCNJ11, CDKAL1, SLC30A8, and CDKN2B with type 2 diabetes mellitus in the Russian population
Aleksey G. Nikitin, Viktor Y. Potapov, Olga I. Brovkina, Ekaterina O. Koksharova, Dmitry S. Khodyrev, Yury I. Philippov, Marina S. Michurova, Minara S. Shamkhalova, Olga K. Vikulova, Svetlana A. Smetanina, Lyudmila A. Suplotova, Irina V. Kononenko, Viktor Y. Kalashnikov, Olga M. Smirnova, Alexander Y. Mayorov, Valery V. Nosikov, Alexander V. Averyanov, Marina V. Shestakova
https://doi.org/10.7717/peerj.3414 PubMed 28717589
June 29, 2017
BMI prediction within a Korean population
Jin Sol Lee, Hyun Sub Cheong, Hyoung-Doo Shin
https://doi.org/10.7717/peerj.3510 PubMed 28674662
April 25, 2017
Contribution of temporal data to predictive performance in 30-day readmission of morbidly obese patients
Petra Povalej Brzan, Zoran Obradovic, Gregor Stiglic
https://doi.org/10.7717/peerj.3230 PubMed 28462037
March 21, 2017
Comparison of consumption behavior and appetite sensations among patients with type 2 diabetes mellitus after bariatric surgery
Chun Yeh, Hsien-Hao Huang, Shu-Chun Chen, Tung-Fang Chen, Kong-Han Ser, Chih-Yen Chen
https://doi.org/10.7717/peerj.3090 PubMed 28344903
September 20, 2016
Aggressive nutrition in extremely low birth weight infants: impact on parenteral nutrition associated cholestasis and growth
Andreas Repa, Ruth Lochmann, Lukas Unterasinger, Michael Weber, Angelika Berger, Nadja Haiden
https://doi.org/10.7717/peerj.2483 PubMed 27688976
October 13, 2015
Successful childhood obesity management in primary care in Canada: what are the odds?
Stefan Kuhle, Rachel Doucette, Helena Piccinini-Vallis, Sara F.L. Kirk
https://doi.org/10.7717/peerj.1327 PubMed 26623175
July 7, 2015
Neurodevelopmental problems and extremes in BMI
Nóra Kerekes, Armin Tajnia, Paul Lichtenstein, Sebastian Lundström, Henrik Anckarsäter, Thomas Nilsson, Maria Råstam
https://doi.org/10.7717/peerj.1024 PubMed 26207189
February 19, 2013
Phenotypic characterization of patients with deletions in the 3’-flanking SHOX region
Sarina G. Kant, Sander J. Broekman, Caroline C. de Wit, Marloes Bos, Sitha A. Scheltinga, Egbert Bakker, Wilma Oostdijk, Hetty J. van der Kamp, Erik W. van Zwet, Annemieke H. van der Hout, Jan M. Wit, Monique Losekoot
https://doi.org/10.7717/peerj.35 PubMed 23638371