University of Glasgow
School of Physics and Astronomy
My current research focusses on real-time image processing for the synchronisation of 3D images of the, in vivo, beating zebrafish heart as Research Assistant to Dr Jonathan Taylor.
The zebrafish (Danio Rerio) is popular model organism in microscopy due to it's optical transparency and the wide range of fluorescence transgenic lines now available. Zebrafish are even more attractive as models for cardiac developmental biology due to the similarity to early mammalian heart development and, in cardiac injury and repair, due to their amazing ability to regenerate heart tissue.
Despite all these benefits, the constant motion of the heart is a major obstacle to live imaging and, in the past, fish have been fixed or their heartbeats have been pharmaceutically slowed down. Our research aims to develop the hardware and software needed to create truly synchronised 3D images of whole heartbeats over long time periods so that the long term effects of drugs or injury on heart and vasculature can be elucidated.
To this end we collaborate with researchers from the Centre for Cardiovascular Science at University of Edinburgh, where we're working towards detailed long-term studies of heart morphology and structure both during development and regeneration. This research is funded by the British Heart Foundation.
Durham University
October 2013
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March 2017
School of Engineering and Computing Sciences
I submitted my PhD in Computer Science from Durham University in 2017. My thesis is titled "Mathematical Morphology for Quantification in Biological & Medical Analysis" and features various mathematical approaches to image enhancement, feature detection and measurement of complex systems.
My PhD research focussed on the interdisciplinary field of bioimage informatics, using advanced and novel computer science and mathematical approaches to analyse, evaluate, manage and visualise biological and biomedical data from imaging, e.g. lightsheet microscopy.
I collaborated closely with scientists in the biological and medical sciences, optics, image processing and computer vision to develop novel methods for the analyse of large scale, high throughput and complex image sets.
