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Dr. Can Küçük currently works at İzmir Biomedicine and Genome Center (IBG) and Dokuz Eylul University in Turkey as an associate professor and independent PI with his own research group. He has authored research articles in high profile journals on molecular pathobiology or diagnostics of NK and/or T cell malignancies.
Dr. Küçük graduated from the Department of Molecular Biology and Genetics at Middle East Technical University (METU) in 2005. He got his Ph.D degree in Cancer Biology and Oncology from Eppley Institute for Research in Cancer and Allied Diseases at University of Nebraska Medical Center (UNMC) in 2012. He worked as a post-doc in the Department of Pathology at UNMC and then at City of Hope Medical Center.
His group investigates the etiology of lymphoid malignancies using personalized medicine approach. In particular, whole-exome sequencing or whole transcriptome sequencing are applied on tumor samples to identify aberrant genes or pathways leading to development of these neoplasms. His group aims to:
1) identify novel recurrent aberrations that can be targeted by rational drugs.
2) develop companion diagnostics methodologies for personalized medicine
3) identify novel biomarkers of diagnosis, prognosis or disease management.
The other areas of research interest in Dr. Küçük lab can be described as follows:
a) Rare diseases