During my PhD, my research was focused on understanding the structural basis for the stability of family 10 xylanase from Bacillus Sp. under poly-extreme conditions and published four research papers. I have good experience of plant tissue culture, protein purification from transgenic plants, proteomics analysis of plant proteins. Besides, I have received a US patent for developing a system using signal peptide of above mentioned xylanase to secrete out foreign proteins from chloroplast and target them to desired sub-cellular organelles.
I received Arturo Falaschi ICGEB postdoctoral fellowship for three years to carryout research on TDP-43 which is a splicing factor and also clinically important protein in various neurodegenerative diseases.
During my second postdoc at NYU medical center, i have been working on generating tankyrase KO human cell lines using CRISPR-Cas9 and to identify novel protein targets of tankyrase mediated degradation using proteomics tool.