Amit Bhardwaj

Amit Bhardwaj


Summary

During my PhD, my research was focused on understanding the structural basis for the stability of family 10 xylanase from Bacillus Sp. under poly-extreme conditions and published four research papers. I have good experience of plant tissue culture, protein purification from transgenic plants, proteomics analysis of plant proteins. Besides, I have received a US patent for developing a system using signal peptide of above mentioned xylanase to secrete out foreign proteins from chloroplast and target them to desired sub-cellular organelles.
I received Arturo Falaschi ICGEB postdoctoral fellowship for three years to carryout research on TDP-43 which is a splicing factor and also clinically important protein in various neurodegenerative diseases.
During my second postdoc at NYU medical center, i have been working on generating tankyrase KO human cell lines using CRISPR-Cas9 and to identify novel protein targets of tankyrase mediated degradation using proteomics tool.

Biochemistry Biotechnology Cell Biology Microbiology Molecular Biology Plant Science

Work details

Postdoctoral fellow

NYU School of Medicine
March 2014
molecular Pathogenesis
To study tankyrase roles in telomere length maintenance, telomere cohesion and WNT signaling

PhD Student

International center for genetic engineering and biotechnology
June 2005 - October 2010
Plant Transformation Group
To understand the structural basis for the stability of family 10 xylanase under poly-extreme conditions.

Postdoctoral fellow

International center for genetic engineering and biotechnology
November 2010 - October 2013
Molecular pathology
To study the TDP-43 interaction with its RNA targets.

Websites

PeerJ Contributions